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CDK5 — PPARA
Text-mined interactions from Literome
Choi et al., Nature 2011
(Disease Models, Animal...) :
These data illustrate that new classes of antidiabetes drugs can be developed by specifically targeting the
Cdk5 mediated phosphorylation of
PPAR?
Kono et al., Mol Endocrinol 2012
(Diabetes Mellitus, Experimental) :
We conclude that pioglitazone modulates SERCA2b expression through direct transcriptional regulation of the gene and indirectly through prevention of
CDK5 induced phosphorylation of
PPAR-?