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CXCL10 — EGF
Text-mined interactions from Literome
Shiraha et al., J Cell Biol 1999
:
We report here that
IP-10 inhibited
EGF- and heparin binding EGF-like growth factor induced Hs68 human dermal fibroblast motility in a dose dependent manner ( to 52 % and 44 %, respectively, at 50 ng/ml IP-10 ), whereas IP-10 had no effect on either basal or EGFR mediated mitogenesis ( 96 +/- 15 % at 50 ng/ml ) ...
IP-10 also
prevented EGF- induced calpain activation ( reduced by 71 +/- 7 % )
Azenshtein et al., Cancer Lett 2005
(Breast Neoplasms...) :
EGF potently
up-regulated CXCL8 secretion by breast tumor cells, and its effect was promoted by a consecutive treatment of the cells by estrogen and progesterone
Haim et al., Neoplasia (New York, N.Y.) 2011
(Breast Neoplasms) :
We found that stimulation by
EGF alone
induced the release of
CXCL8 through signaling pathways involving ErbB2, ErbB1, Erk, and phosphoinositide 3-kinase (PI3K)
Son et al., Journal of inflammation (London, England) 2013
:
Finally, CCL20 and
CXCL8 responded synergistically in
response to
EGF and TNF in OVCAR-3 and SKOV-3 cells