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EPHB2 — MUC5AC
Text-mined interactions from Literome
Słomiany et al., J Physiol Pharmacol 2005
:
The
gastric mucin secretory responses to isoproterenol, furthermore, were
inhibited by PP2, a selective inhibitor of tyrosine kinase Src responsible for ligand independent EGFR autophosphorylation, but not by
ERK inhibitor, PD98059
Ha et al., J Immunol 2007
:
A novel role for IkappaB kinase (IKK) alpha and IKKbeta in
ERK dependent up-regulation of
MUC5AC mucin transcription by Streptococcus pneumoniae
Huang et al., Biochem Biophys Res Commun 2007
:
Moreover, activation of both p38 and
ERK is
required for synergistic induction of
MUC5AC by NTHi and EGF
Tadaki et al., J Immunol 2009
(MAP Kinase Signaling System) :
This synergistic effect on
MUC5AC production may be
due to enhanced activation of
ERK through inhibition of MKP3 by poly ( I:C )
Lim et al., American journal of translational research 2009
:
In the present study, we showed that positive
regulation of
MUC5AC mucin expression by
ERK1/2 is dependent on Ras-Raf-1 signaling pathway, whereas the negative regulation of MUC5AC expression by JNK1/2 is dependent on MEKK3 ...
Ras-Raf1-ERK1/2 dependent AP-1 activation positively
regulates MUC5AC mucin induction by S. pneumoniae, whereas MEKK3-JNK1/2 dependent AP-1 activation negatively regulates it
Li et al., Mol Biol Rep 2012
(MAP Kinase Signaling System) :
p-ERK1/2 increased significantly in response to compressive stress and PD-98059 could
attenuated stress induced
MUC5AC expression
Morinaga et al., Can J Microbiol 2012
(MAP Kinase Signaling System) :
Inhibitors of
ERK and JNK, but not p38, dose-dependently
inhibited the induction of
MUC5AC by live L. pneumophila
Lee et al., J Biol Chem 2012
(MAP Kinase Signaling System...) :
We previously reported that S. pneumoniae up-regulates
MUC5AC expression in a MAPK
ERK dependent manner ... We also found that MAPK phosphatase-1 (MKP-1) negatively regulates S. pneumoniae induced
ERK dependent
MUC5AC up-regulation