Gene interactions and pathways from curated databases and text-mining

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GTF2F1 — SP1

Pathways - manually collected, often from reviews:

  • FastForward regulation: SP1 → GTF2F1 (transcriptional regulation, unknown)
    Evidence: DNABINDING

Text-mined interactions from Literome

Yeh et al., Nucleic Acids Res 2006 : The transcription factor ( TF ) Sp1 is a well-known RNA polymerase II transcription activator that binds to GC-rich recognition sites in a number of essential cellular and viral promoters
Farnham et al., Gene Expr 1991 : Sp1 activation of RNA polymerase II transcription complexes involves a heat-labile DNA binding component
Pagtakhan et al., Virology 1997 : We suggest that these interactions, rather than direct Tat/Sp1 binding, result in highly processive RNA polymerase II complexes and full-length viral transcripts