Human Gene EXO5 (ENST00000415550.6_5) from GENCODE V47lift37
  Description: exonuclease 5, transcript variant 9 (from RefSeq NM_001346953.2)
Gencode Transcript: ENST00000415550.6_5
Gencode Gene: ENSG00000164002.12_13
Transcript (Including UTRs)
   Position: hg19 chr1:40,974,439-40,981,710 Size: 7,272 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr1:40,980,217-40,981,338 Size: 1,122 Coding Exon Count: 1 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:40,974,439-40,981,710)mRNA (may differ from genome)Protein (373 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.97 RPKM in Spleen
Total median expression: 99.89 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -146.80405-0.362 Picture PostScript Text
3' UTR -92.20372-0.248 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  AK021507 - Homo sapiens cDNA FLJ11445 fis, clone HEMBA1001375.
AK094092 - Homo sapiens cDNA FLJ36773 fis, clone ADRGL2000142.
AK024797 - Homo sapiens cDNA: FLJ21144 fis, clone CAS07955.
BC021969 - Homo sapiens defects in morphology 1 homolog (S. cerevisiae), mRNA (cDNA clone MGC:14947 IMAGE:3952573), complete cds.
AK023245 - Homo sapiens cDNA FLJ13183 fis, clone NT2RP3004145.
JD336584 - Sequence 317608 from Patent EP1572962.
JD462025 - Sequence 443049 from Patent EP1572962.
JD177049 - Sequence 158073 from Patent EP1572962.
JD407030 - Sequence 388054 from Patent EP1572962.
JD462582 - Sequence 443606 from Patent EP1572962.
LF206601 - JP 2014500723-A/14104: Polycomb-Associated Non-Coding RNAs.
JD519290 - Sequence 500314 from Patent EP1572962.
HQ448143 - Synthetic construct Homo sapiens clone IMAGE:100071528; CCSB006634_02 chromosome 1 open reading frame 176 (C1orf176) gene, encodes complete protein.
KJ899475 - Synthetic construct Homo sapiens clone ccsbBroadEn_08869 DEM1 gene, encodes complete protein.
JD474305 - Sequence 455329 from Patent EP1572962.
LF356439 - JP 2014500723-A/163942: Polycomb-Associated Non-Coding RNAs.
LF356438 - JP 2014500723-A/163941: Polycomb-Associated Non-Coding RNAs.
LF356437 - JP 2014500723-A/163940: Polycomb-Associated Non-Coding RNAs.
AF086542 - Homo sapiens full length insert cDNA clone ZE09H03.
JD172117 - Sequence 153141 from Patent EP1572962.
JD093805 - Sequence 74829 from Patent EP1572962.
MA442178 - JP 2018138019-A/14104: Polycomb-Associated Non-Coding RNAs.
MA592016 - JP 2018138019-A/163942: Polycomb-Associated Non-Coding RNAs.
MA592015 - JP 2018138019-A/163941: Polycomb-Associated Non-Coding RNAs.
MA592014 - JP 2018138019-A/163940: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000415550.1, ENST00000415550.2, ENST00000415550.3, ENST00000415550.4, ENST00000415550.5, EXO5 , NM_001346953, uc319ljh.1, uc319ljh.2, X6RK18, X6RK18_HUMAN
UCSC ID: ENST00000415550.6_5
RefSeq Accession: NM_001346953.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.