ID:PIHD1_HUMAN DESCRIPTION: RecName: Full=PIH1 domain-containing protein 1; AltName: Full=Nucleolar protein 17 homolog; SIMILARITY: Belongs to the PIH1 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NWS0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding GO:0005515 protein binding GO:0019901 protein kinase binding GO:0042393 histone binding GO:0051117 ATPase binding GO:0051219 phosphoprotein binding GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding
Biological Process: GO:0000492 box C/D snoRNP assembly GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly GO:0006338 chromatin remodeling GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006364 rRNA processing GO:0030855 epithelial cell differentiation GO:0031334 positive regulation of protein complex assembly GO:0048254 snoRNA localization GO:0051569 regulation of histone H3-K4 methylation GO:0071169 establishment of protein localization to chromatin GO:0071902 positive regulation of protein serine/threonine kinase activity GO:0090240 positive regulation of histone H4 acetylation GO:1900110 negative regulation of histone H3-K9 dimethylation GO:1900113 negative regulation of histone H3-K9 trimethylation GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter GO:1902661 positive regulation of glucose mediated signaling pathway GO:1904263 positive regulation of TORC1 signaling GO:2000617 positive regulation of histone H3-K9 acetylation GO:2000619 negative regulation of histone H4-K16 acetylation GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:1903939 regulation of TORC2 signaling