Human Gene RCN1 (ENST00000054950.4_5) from GENCODE V47lift37
  Description: reticulocalbin 1 (from RefSeq NM_002901.4)
Gencode Transcript: ENST00000054950.4_5
Gencode Gene: ENSG00000049449.10_8
Transcript (Including UTRs)
   Position: hg19 chr11:32,112,620-32,127,268 Size: 14,649 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr11:32,112,743-32,126,018 Size: 13,276 Coding Exon Count: 6 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:32,112,620-32,127,268)mRNA (may differ from genome)Protein (331 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: RCN1
Diseases sorted by gene-association score: nephrogenic systemic fibrosis (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 83.33 RPKM in Cells - Cultured fibroblasts
Total median expression: 773.59 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -35.20123-0.286 Picture PostScript Text
3' UTR -308.201250-0.247 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  AK293652 - Homo sapiens cDNA FLJ55835 complete cds, highly similar to Reticulocalbin-1 precursor.
AK129791 - Homo sapiens cDNA FLJ26280 fis, clone DMC06770, highly similar to RETICULOCALBIN 1 PRECURSOR.
BC010120 - Homo sapiens reticulocalbin 1, EF-hand calcium binding domain, mRNA (cDNA clone MGC:19541 IMAGE:3836263), complete cds.
D42073 - Homo sapiens mRNA for reticulocalbin, complete cds.
FJ224346 - Homo sapiens epididymis secretory protein Li 84 (HEL-S-84) mRNA, complete cds.
JD550664 - Sequence 531688 from Patent EP1572962.
CU679627 - Synthetic construct Homo sapiens gateway clone IMAGE:100018971 5' read RCN1 mRNA.
DQ892928 - Synthetic construct clone IMAGE:100005558; FLH190928.01X; RZPDo839F0676D reticulocalbin 1, EF-hand calcium binding domain (RCN1) gene, encodes complete protein.
DQ896177 - Synthetic construct Homo sapiens clone IMAGE:100010637; FLH190924.01L; RZPDo839F0666D reticulocalbin 1, EF-hand calcium binding domain (RCN1) gene, encodes complete protein.
KJ891990 - Synthetic construct Homo sapiens clone ccsbBroadEn_01384 RCN1 gene, encodes complete protein.
JD025092 - Sequence 6116 from Patent EP1572962.
JD138890 - Sequence 119914 from Patent EP1572962.
JD203515 - Sequence 184539 from Patent EP1572962.
AK094360 - Homo sapiens cDNA FLJ37041 fis, clone BRACE2011892, highly similar to RETICULOCALBIN 1 PRECURSOR.
JD295758 - Sequence 276782 from Patent EP1572962.
JD249471 - Sequence 230495 from Patent EP1572962.
AY423728 - Homo sapiens proliferation-inducing gene 20 protein mRNA, complete cds, alternatively spliced.
AK126419 - Homo sapiens cDNA FLJ44455 fis, clone UTERU2023687, highly similar to RETICULOCALBIN 1 PRECURSOR.
JD449121 - Sequence 430145 from Patent EP1572962.
JD545373 - Sequence 526397 from Patent EP1572962.
JD310260 - Sequence 291284 from Patent EP1572962.
JD528624 - Sequence 509648 from Patent EP1572962.
JD489789 - Sequence 470813 from Patent EP1572962.
JD242283 - Sequence 223307 from Patent EP1572962.
JD503863 - Sequence 484887 from Patent EP1572962.
JD044204 - Sequence 25228 from Patent EP1572962.
JD315525 - Sequence 296549 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000054950.1, ENST00000054950.2, ENST00000054950.3, HEL-S-84 , NM_002901, uc317cab.1, uc317cab.2, V9HW95, V9HW95_HUMAN
UCSC ID: ENST00000054950.4_5
RefSeq Accession: NM_002901.4

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.