ID:SYCP2_HUMAN DESCRIPTION: RecName: Full=Synaptonemal complex protein 2; Short=SCP-2; AltName: Full=Synaptonemal complex lateral element protein; Short=hsSCP2; FUNCTION: Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements (By similarity). SUBUNIT: Heterodimer with SYCP3. Interacts with SYCP3, SMC1A and SMC3 (By similarity). SUBCELLULAR LOCATION: Nucleus (By similarity). Note=In axial/lateral elements of the tripartite segments of synaptonemal complexes (By similarity). SIMILARITY: Belongs to the SYCP2 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 48371 - ARM repeat 50729 - PH domain-like
ModBase Predicted Comparative 3D Structure on Q9BX26
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
