◀ Back to CASP16
CASP16 — IL11
Text-mined interactions from Literome
Guo et al., Blood 2003
:
In the present study we confirm that Fas signaling induces both phenotypic and functional maturation of murine DCs, and we demonstrate that phenotypic maturation is associated with phosphorylation of extracellular signal regulated kinase ( ERK ) 1/2,
activation of
caspase-1 , and secretion of
interleukin-beta ( IL-1beta )
Kiessling et al., J Biol Chem 2004
:
However,
IL-11 stimulation
resulted in a dose dependent tyrosine phosphorylation of Akt, a decreased activation of
caspase-9 , and a reduced induction of apoptosis in cultured CEC
Wang et al., Ann Thorac Surg 2005
(Reperfusion Injury) :
Myocardial tissue was then assessed for products of p38 MAPK activation, expression of tumor necrosis factor,
interleukin-1beta and interleukin-6, and
activation of caspase-1,
caspase-3 and caspase-11
Shushanov et al., Bull Exp Biol Med 2010
:
Insulin-like growth factor-1 and insulin inhibit
caspase-3/7 activation
initiated by
interleukin-1ß in the rat eye retinal neurons
Zhang et al., J Immunol 2011
(Demyelinating Diseases...) :
In oligodendrocyte progenitor cell ( OPC ) cultures,
IL-11 restricted
caspase 9
activation and apoptosis, and it increased myelination in OPC-neuron cocultures ... In contrast,
IL-11 augmented
caspase activation and apoptosis in cultures of CD11c ( + ) DCs, but not in CD11b ( + ) or CD3 ( + ) cells
Liao et al., Inflamm Res 2013
:
Lipopolysaccharide/adenosine triphosphate mediated signal transduction in the regulation of NLRP3 protein expression and
caspase-1 mediated
interleukin-1ß secretion