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IL13 — TCF23
Text-mined interactions from Literome
Madden et al., J Immunol 2002
:
Binding of IL-4 by either the type 1 or 2 IL-4R, or of
IL-13 by the type 2 IL-4R,
initiates Jak dependent tyrosine phosphorylation of the IL-4Ralpha-chain and the
transcription factor , STAT6
McDermott et al., Trends Mol Med 2002
(Familial Mediterranean Fever...) :
Disorders of
interleukin-1 processing and of
regulation of nuclear factor kappaB
transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Sheikh et al., Hepatology 2008
(Hepatitis C...) :
This
transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha),
interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008
(Arthritis, Rheumatoid...) :
IRF-4 binding protein
inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4
transcription factor
Saraiva et al., Immunity 2009
:
Interleukin-10 production by Th1 cells requires
interleukin-12 induced STAT4
transcription factor and ERK MAP kinase activation by high antigen dose
Sung et al., J Biol Chem 1993
:
Stimulation of
interleukin-1 gene transcription may be
caused by the stimulation of
transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors
Palmer-Crocker et al., J Clin Invest 1996
:
Furthermore, both IL-4 and
IL-13 induce binding of the Stat6
transcription factor to a consensus sequence oligonucleotide
Manna et al., J Immunol 1998
:
TNF induced activation of another nuclear
transcription factor , AP-1, was
suppressed by
IL-13
Lentsch et al., J Immunol 1999
(Acute Disease...) :
In the
presence of
anti-IL-13 , activation of the
transcription factor , NF-kappaB, was significantly increased in lung