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BAK1 — BCL2L1

Pathways - manually collected, often from reviews:

• BioCarta role of mitochondria in apoptotic signaling: BCL-XL/BCL-2/BAK complex (BCL2L1-BCL2-BAK1) → Apaf-1 (APAF1) (translocation, activates)
• BioCarta role of mitochondria in apoptotic signaling: BCL-2 (BCL2) → BCL-XL/BCL-2/BAK complex (BCL2L1-BCL2-BAK1) (modification, collaborate)
  
• BioCarta role of mitochondria in apoptotic signaling: BCL-XL (BCL2L1) → BCL-XL/BCL-2/BAK complex (BCL2L1-BCL2-BAK1) (modification, collaborate)
  
• BioCarta role of mitochondria in apoptotic signaling: BCL-XL (BCL2L1) → BAK (BAK1) (modification, collaborate)
• BioCarta role of mitochondria in apoptotic signaling: BCL-XL/BCL-2/BAK complex (BCL2L1-BCL2-BAK1) → BAK (BAK1) (modification, collaborate)
• BioCarta role of mitochondria in apoptotic signaling: BCL-XL/BCL-2/BAK complex (BCL2L1-BCL2-BAK1) → cytochrome C (CYCS) (translocation, activates)
• WikiPathways Apoptosis Modulation and Signaling: BCL2L1 → BAK1 (activation)
• WikiPathways Apoptosis Modulation and Signaling: BCL2L1 → BAK1 (unknown)
• WikiPathways Apoptosis: BAK1 → BCL2L2/BCL2/BCL2L1/MCL1 (inhibition)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: BAK1 — BCL2L1 Griffiths et al., J Cell Biol 1999*, Holinger et al., J Biol Chem 1999*, Hammond et al., J Biol Chem 2001*, Sattler et al., Science 1997*
• IRef Bind_translation Interaction: BAK1 — BCL2L1 (unspecified method) Hammond et al., J Biol Chem 2001*
• IRef Bind_translation Interaction: BAK1 — BCL2L1 (coimmunoprecipitation) Hammond et al., J Biol Chem 2001*, Sattler et al., Science 1997*
• IRef Bind_translation Interaction: BAK1 — BCL2L1 (competition binding) Holinger et al., J Biol Chem 1999*, Hammond et al., J Biol Chem 2001*
• IRef Bind_translation Interaction: BAK1 — BCL2L1 (coimmunoprecipitation) Griffiths et al., J Cell Biol 1999*, Hammond et al., J Biol Chem 2001*
• IRef Biogrid Interaction: BAK1 — BCL2L1 (direct interaction, unspecified method) Willis et al., Genes Dev 2005*
• IRef Biogrid Interaction: BAK1 — BCL2L1 (physical association, affinity chromatography technology) Rual et al., Nature 2005
• IRef Biogrid Interaction: BAK1 — BCL2L1 (direct interaction, two hybrid) Rual et al., Nature 2005
• IRef Biogrid Interaction: BAK1 — BCL2L1 (direct interaction, unspecified method) Zhang et al., Anal Biochem 2002*
• IRef Biogrid Interaction: BAK1 — BCL2L1 (direct interaction, fluorescent resonance energy transfer) Whitfield et al., Anal Biochem 2003*
• IRef Biogrid Interaction: BAK1 — BCL2L1 (physical association, affinity chromatography technology) Willis et al., Genes Dev 2005*
• IRef Biogrid Interaction: BAK1 — BCL2L1 (direct interaction, pull down) Degterev et al., Nat Cell Biol 2001*
• IRef Biogrid Interaction: BAK1 — BCL2L1 (direct interaction, two hybrid) Venkatesan et al., Nat Methods 2009
• IRef Innatedb Interaction: Complex of BCL2L1-BAX-BAK1-BAX-BAK1 (unknown, -) Plötz et al., Cell Death Differ 2012*
• IRef Intact Interaction: BAK1 — BCL2L1 (physical association, two hybrid array) Venkatesan et al., Nat Methods 2009
• IRef Intact Interaction: BAK1 — BCL2L1 (physical association, scintillation proximity assay) Whitfield et al., Anal Biochem 2003*
• IRef Intact Interaction: BAK1 — BCL2L1 (physical association, homogeneous time resolved fluorescence) Whitfield et al., Anal Biochem 2003*
• IRef Intact Interaction: BAK1 — BCL2L1 (direct interaction, anti bait coimmunoprecipitation) Willis et al., Genes Dev 2005*
• IRef Intact Interaction: BAK1 — BCL2L1 (physical association, anti tag coimmunoprecipitation) Willis et al., Genes Dev 2005*
• IRef Intact Interaction: BAK1 — BCL2L1 (direct interaction, surface plasmon resonance) Willis et al., Genes Dev 2005*
• IRef Intact Interaction: BAK1 — BCL2L1 (physical association, two hybrid pooling approach) Rual et al., Nature 2005
• IRef Intact Interaction: BAK1 — BCL2L1 (physical association, two hybrid pooling approach) Venkatesan et al., Nat Methods 2009
• IRef Intact Interaction: Complex of BCL2L1-BECN1-BAK1 (physical association, fluorescence polarization spectroscopy) Maiuri et al., EMBO J 2007*
• IRef Intact Interaction: Complex of BAK1-BCL2L1-BAK1 (physical association, fluorescence polarization spectroscopy) Maiuri et al., EMBO J 2007*
• IRef Intact Interaction: Complex of BBC3-BAK1-BCL2L1-BCL2L11 (association, anti tag coimmunoprecipitation) Wei et al., Cancer Cell 2012*
• IRef Ophid Interaction: BAK1 — BCL2L1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: BAK1 — BCL2L1 (aggregation, confirmational text mining) Degterev et al., Nat Cell Biol 2001*