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IL8 — INS

Text-mined interactions from Literome

Mabley et al., Br J Pharmacol 2001 (Diabetes Mellitus, Experimental) : In vitro the cytokine combination ; interleukin-1beta , tumor necrosis factor-alpha and interferon-gamma inhibited glucose stimulated insulin secretion from isolated rat islets of Langerhans and decreased RIN-5F cell viability
Straczkowski et al., Cardiovascular diabetology 2003 : Increase in plasma IL-8 might be both insulin mediated ( during clamp ) and glucose mediated ( during OGTT )
Rabinovitch et al., Diabetologia 1992 : The individual cytokines, interleukin 1 ( 1 U/ml ), tumour necrosis factor ( 10 ( 2 ) U/ml ), and interferon gamma ( 10 ( 2 ) U/ml ) inhibited insulin release but did not increase islet malondialdehyde levels
Fain et al., Metabolism 2005 : Insulin enhances vascular endothelial growth factor, interleukin-8 , and plasminogen activator inhibitor 1 but not interleukin-6 release by human adipocytes
Yelich et al., Pancreas 1992 : Effects of endotoxin and interleukin-1 on glucagon and insulin secretion from the perfused rat pancreas
Zawalich et al., Mol Cell Endocrinol 1991 : Influence of staurosporine, nitrendipine and monooleoylglycerol on interleukin-1 induced insulin secretion and phosphoinositide hydrolysis
Johannesen et al., Acta Endocrinol (Copenh) 1990 : During beta-cell stimulation with tolbutamide, interleukin 1 beta caused inhibition of insulin accumulation to 36 +/- 9 % of control
Shimizu et al., J Endocrinol Invest 1991 : Involvement of interleukin-1 in the inhibition of in vivo insulin release : possible role of adrenal glands
Uehara et al., Eur J Pharmacol 1991 (Hyperinsulinism) : With the aim of studying the mechanism by which peripherally injected interleukin-1 increases the serum levels of insulin in conscious rats, the effects of indomethacin, a cyclooxygenase inhibitor, on interleukin-1 induced hyperinsulinemia were examined using male Wistar rats implanted with intra-atrial cannulas ... It was also found that this insulin response to interleukin-1 was dose related ... Pretreatment with indomethacin ( 3 mg/kg body weight ), however, completely blocked the interleukin-1 induced stimulation of insulin secretion
Grob et al., J Biol Chem 1990 : The binding of MDNCF/IL-8 to human neutrophils is not inhibited by interleukin-1 alpha, tumor necrosis factor-alpha, insulin , or epidermal growth factor
Parazzoli et al., J Biol Chem 2012 : Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1ß induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets
Helqvist et al., Acta Endocrinol (Copenh) 1989 : Treatment with 10 mumol/l of verapamil ( a potent blocker of the voltage dependent calcium channel ) tended to suppress the inhibitory effect of interleukin 1 on insulin release from rat islets, suggesting protection against cytotoxicity
Hansen et al., Biomed Biochim Acta 1988 : Effect of interleukin-1 on the biosynthesis of proinsulin and insulin in isolated rat pancreatic islets
Sandler et al., Endocrinology 1987 : Inhibitory effects of interleukin 1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets
Rabinovitch et al., Diabetologia 1994 : The individual cytokines, interleukin 1 ( 10 U/ml ), tumour recrosis factor ( 10 ( 3 ) U/ml ) and interferon gamma ( 10 ( 3 ) U/ml ) inhibited insulin release from rat islets, but did not cause DNA fragmentation or destroy islet cells ; by contrast, combination of the three cytokines induced DNA fragmentation and islet-cell death
Bian et al., J Leukoc Biol 1996 : High concentrations of glucose ( 20 mM ; 360 mg/dl ) increased GHSA induced hRPE IL-8 and MCP-1 secretion, whereas added insulin ( 0.5 ng/mL ) inhibited IL-8 but not MCP-1 protein secretion and mRNA expression