Gene interactions and pathways from curated databases and text-mining

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BID — MAPK3

Text-mined interactions from Literome

Qiao et al., Mol Biol Cell 2001 (MAP Kinase Signaling System) : Inhibition of bile acid induced MAPK signaling enhanced the cleavage of BID and release of cytochrome c from mitochondria, which were all blocked by IETD
Wang et al., Endocrinology 2007 : In conclusion, our data suggest that both p38 MAPK and iNOS are involved in IFN-gamma/IL-1beta induced sensitization of the thyroid cells to Fas mediated apoptosis via the activation of caspases 3, 7, and 10 and that this pathway may be further activated by BID