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MAPK3 — MAPKAPK5
Text-mined interactions from Literome
Martel-Pelletier et al., Arthritis Rheum 1999
(Osteoarthritis) :
Mitogen activated protein kinase and nuclear factor kappaB together regulate interleukin-17 induced nitric oxide production in human osteoarthritic chondrocytes : possible role of transactivating factor
mitogen activated protein kinase activated proten kinase (
MAPKAPK )
Aberg et al., J Biol Chem 2006
:
Regulation of
MAPK activated protein kinase 5 activity and subcellular localization by the atypical
MAPK ERK4/MAPK4
Kant et al., J Biol Chem 2006
:
Characterization of the atypical
MAPK ERK4 and its
activation of the MAPK activated protein kinase
MK5
Kostenko et al., Cell Mol Life Sci 2011
:
The
mitogen activated protein kinase activated protein kinase
MK5 is ubiquitously expressed in vertebrates and is implicated in cell proliferation, cytoskeletal remodeling, and anxiety behavior
Kostenko et al., Cell Mol Life Sci 2011
:
Serine residue 115 of
MAPK activated protein kinase
MK5 is crucial for its PKA regulated nuclear export and biological function
Shiryaev et al., Journal of molecular signaling 2011
:
The MAPKAPKs MK2, MK3 and MK5 are closely related, but MK2 and MK3 are the major downstream targets of the p38MAPK pathway, while
MK5 can be
activated by the atypical MAPK ERK3 and ERK4, protein kinase A (PKA), and maybe
p38MAPK
Kostenko et al., World journal of biological chemistry 2011
:
Physiological roles of
mitogen-activated-protein-kinase activated
p38 regulated/activated protein kinase
Komatsu et al., Arch Biochem Biophys 1997
:
The protein kinase activity of
GST-MAPKAPK-4 was
activated by
MAPK and this enabled the kinase to phosphorylate both glycogen synthase N-terminal peptide and the regulatory light chain of myosin II in vitro