UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to MAPK3

MAPK3 — MYLK

Pathways - manually collected, often from reviews:

BioCarta mcalpain and friends in cell motility: ERK1 (MAPK3) → myosin light chain protein kinase (MYLK) (modification, activates)
BioCarta erk and pi-3 kinase are necessary for collagen binding in corneal epithelia: ERK1 (MAPK3) → myosin light chain protein kinase (MYLK) (modification, activates)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Hprd Interaction: MAPK3 — MYLK (in vitro) Nguyen et al., J Cell Biol 1999 *
IRef Ophid Interaction: MAPK3 — MYLK (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
IRef Ophid Interaction: MAPK3 — MYLK (aggregation, confirmational text mining) Nguyen et al., J Cell Biol 1999 *

Text-mined interactions from Literome

Vorotnikov et al., Tsitologiia 2000 : Phosphopeptide mapping suggests the involvement of mitogen activated protein ( MAP ) kinases in phosphorylation of MLCK in situ
Costantini et al., J Surg Res 2009 (Burns) : We hypothesized that ( 1 ) severe burn up-regulates p38 MAPK activation and results in increased intestinal permeability via augmented expression of MLCK, and ( 2 ) inhibition of p38 MAPK will prevent the burn induced increase in MLCK expression, resulting in improved intestinal barrier integrity
Rossi et al., J Neurosci Res 2011 (Brain Injuries...) : Albumin causes increased myosin light chain kinase expression in astrocytes via p38 mitogen activated protein kinase