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Mohan et al., Am J Physiol 1999
:
Here we investigate the hypothesis that low shear induced activation of
NF-kappaB is
responsible for enhanced expression of vascular
cell adhesion molecule ( VCAM-1 ) resulting in augmented endothelial cell-monocyte ( EC-Mn ) adhesion and that this activation is dependent on intracellular oxidant activity
Renier et al., J Diabetes Complications 2003
(Diabetes Mellitus, Type 2...) :
The suppressive effect of gliclazide on AGE induced monocyte adhesion to endothelium involves a reduction of
cell adhesion molecule mRNA and protein expression and an
inhibition of
NF-kappaB activation
Liu et al., Am J Physiol Cell Physiol 2003
:
These data indicate that MHb is a potent activator of endothelial cells through
NF-kappaB mediated upregulation of
cell adhesion molecule expression and chemokine and cytokine production
Chatterjee et al., Curr Drug Targets 2008
:
Moreover, in human umbilical vein endothelial cells,
NF-kappaB has been also shown to regulate this enzyme which, in turn,
regulates the gene/protein expression of platelet endothelial
cell adhesion molecule , intercellular cell adhesion molecule and angiogenesis
Eck et al., Mol Cell Biol 1993
:
To investigate the
role of
NF-kappa B in
cell adhesion molecule expression, we treated HL-60 cells with a double stranded oligonucleotide which specifically inhibits NF-kappa B-mediated transcription