Gómez-Hernández et al., Atherosclerosis 2006
(Carotid Artery Diseases) :
In cytokine treated cultured THP-1 , the NF-kappaB inhibitors parthenolide, Bay 11-7082 and PDTC reduced COX-2, mPGES-1 and EP-1/EP-3/EP-4 expression as well as PGE2 levels
Kim et al., Immunology 2006
(Atherosclerosis...) :
Stimulation of GITR caused nuclear factor (NF)-kappaB dependent activation of matrix metalloproteinase-9 (MMP-9) and pro-inflammatory cytokine expression in both the human and mouse monocytic/macrophage cell lines, THP-1 and RAW264.7, respectively