Gene interactions and pathways from curated databases and text-mining

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MAPK11 — SNAP25

Text-mined interactions from Literome

Kohri et al., Eur Respir J 2002 : PA Sup induced MUC5AC mRNA and subsequent protein expression, EGFR and p44/42 MAPK phosphorylation and EGFR mRNA expression
Culmsee et al., Mol Pharmacol 2005 (MAP Kinase Signaling System) : Analysis of the major signaling pathways downstream of TrkA revealed that both SNAP and DPN enhanced phosphorylation of Akt and the mitogen activated kinases ( MAPK ) Erk1/2 ... It was striking that inhibition of the soluble guanylyl cyclase ( sGC ) by 1H- [ 1,2,4 ] oxadiazolo [ 4,3-a ] quinoxalin-1-one ( ODQ ) or protein kinase G ( PKG ) inhibition by ( 9S,10R,12R ) -2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo- [ 1,2,3-fg : 3',2',1'-kl ] pyrrolo [ 3,4-i ] [ 1,6 ] benzodiazocine-10-carboxylic acid methyl ester ( KT5823 ) also blocked the neuroprotective effect of the NO donors, and ODQ clearly attenuated SNAP induced phosphorylation of TrkA, Akt, and MAPK
Størling et al., Diabetologia 2005 : SNAP activated c-Jun N-terminal kinase (JNK) and p38 MAPK , but suppressed the activity of extracellular signal regulated kinase MAPK