UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	CCP1	YKR066C	643	n/a	chrXI 566,655	Mitochondrial cytochrome-c peroxidase degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress
2	ATR1	YML116W	643	n/a	chrXIII 39,010	Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide
3	GRX2	YDR513W	643	n/a	chrIV 1,471,232	Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress
4	DDR48	YMR173W	643	n/a	chrXIII 609,335	DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions contains multiple repeats of the amino acid sequence NNNDSYGS
5	TRX2	YGR209C	643	n/a	chrVII 913,070	Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance
6	GSH1	YJL101C	643	n/a	chrX 235,338	Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis expression induced by oxidants, cadmium, and mercury
7	TSA1	YML028W	643	n/a	chrXIII 220,433	Thioredoxin peroxidase, acts as both a ribosome-associated and free cytoplasmic antioxidant self-associates to form a high-molecular weight chaperone complex under oxidative stress deletion results in mutator phenotype
8	AHP1	YLR109W	643	2.9999999999999996e-100	chrXII 369,046	Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage function in vivo requires covalent conjugation to Urm1p
9	GPX2	YBR244W	643	n/a	chrII 707,772	Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
10	CIN5	YOR028C	643	n/a	chrXV 383,976	Basic leucine zipper (bZIP) transcription factor of the yAP-1 family physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets mediates pleiotropic drug resistance and salt tolerance nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions
11	YNL134C	YNL134C	643	n/a	chrXIV 373,016	Putative protein of unknown function with similarity to dehydrogenases from other model organisms green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced by the DNA-damaging agent MMS
12	YML131W	YML131W	643	n/a	chrXIII 10,746	Putative protein of unknown function with similarity to medium chain dehydrogenase/reductases expression induced by stresses including osmotic shock, DNA damaging agents, and other chemicals GFP-fusion protein localizes to the cytoplasm
13	TSA2	YDR453C	643	n/a	chrIV 1,365,367	Stress inducible cytoplasmic thioredoxin peroxidase cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor deletion enhances the mutator phenotype of tsa1 mutants
14	YDL124W	YDL124W	643	n/a	chrIV 240,728	NADPH-dependent alpha-keto amide reductase reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters member of the aldo-keto reductase (AKR) family
15	GRE2	YOL151W	643	n/a	chrXV 44,208	3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase) stress induced (osmotic, ionic, oxidative, heat shock and heavy metals) regulated by the HOG pathway