Human Gene ACIN1 (ENST00000605057.6_9) from GENCODE V47lift37
  Description: apoptotic chromatin condensation inducer 1, transcript variant 6 (from RefSeq NM_001386863.1)
Gencode Transcript: ENST00000605057.6_9
Gencode Gene: ENSG00000100813.15_17
Transcript (Including UTRs)
   Position: hg19 chr14:23,527,773-23,564,345 Size: 36,573 Total Exon Count: 19 Strand: -
Coding Region
   Position: hg19 chr14:23,528,357-23,564,321 Size: 35,965 Coding Exon Count: 19 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:23,527,773-23,564,345)mRNA (may differ from genome)Protein (1283 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsHGNC
MalacardsMGIPubMedUniProtKBWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: ACIN1
Diseases sorted by gene-association score: breast adenomyoepithelioma (2), breast myoepithelial neoplasm (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 50.28 RPKM in Thyroid
Total median expression: 1585.34 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -0.9024-0.037 Picture PostScript Text
3' UTR -197.40584-0.338 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologGenome BrowserNo ortholog
Gene DetailsGene Details Gene DetailsGene Details 
Gene SorterGene Sorter Gene SorterGene Sorter 
 RGDEnsembl WormBase 
    Protein Sequence 
    Alignment 

-  Descriptions from all associated GenBank mRNAs
  AL050382 - Homo sapiens mRNA; cDNA DKFZp586A032 (from clone DKFZp586A032).
AF124728 - Homo sapiens acinusS' mRNA, complete cds.
AL833228 - Homo sapiens mRNA; cDNA DKFZp667N107 (from clone DKFZp667N107).
BC032770 - Homo sapiens apoptotic chromatin condensation inducer 1, mRNA (cDNA clone IMAGE:3881894), partial cds.
AF124727 - Homo sapiens acinusS mRNA, complete cds.
AB014570 - Homo sapiens mRNA for KIAA0670 protein, partial cds.
AF124726 - Homo sapiens acinusL mRNA, complete cds.
BX247975 - human full-length cDNA clone CS0DF018YA08 of Fetal brain of Homo sapiens (human).
JD381886 - Sequence 362910 from Patent EP1572962.
JD535403 - Sequence 516427 from Patent EP1572962.
JD134822 - Sequence 115846 from Patent EP1572962.
JD392658 - Sequence 373682 from Patent EP1572962.
JD376667 - Sequence 357691 from Patent EP1572962.
JD224789 - Sequence 205813 from Patent EP1572962.
JD149852 - Sequence 130876 from Patent EP1572962.
JD132411 - Sequence 113435 from Patent EP1572962.
JD079862 - Sequence 60886 from Patent EP1572962.
JD044514 - Sequence 25538 from Patent EP1572962.
JD340483 - Sequence 321507 from Patent EP1572962.
JD499314 - Sequence 480338 from Patent EP1572962.
JD197352 - Sequence 178376 from Patent EP1572962.
JD055803 - Sequence 36827 from Patent EP1572962.
JD366046 - Sequence 347070 from Patent EP1572962.
BC140805 - Homo sapiens apoptotic chromatin condensation inducer 1, mRNA (cDNA clone MGC:176482 IMAGE:9021673), complete cds.
AK299034 - Homo sapiens cDNA FLJ50838 partial cds, highly similar to Apoptotic chromatin condensation inducer in thenucleus.
LF210077 - JP 2014500723-A/17580: Polycomb-Associated Non-Coding RNAs.
LF334502 - JP 2014500723-A/142005: Polycomb-Associated Non-Coding RNAs.
LF334503 - JP 2014500723-A/142006: Polycomb-Associated Non-Coding RNAs.
MA445654 - JP 2018138019-A/17580: Polycomb-Associated Non-Coding RNAs.
MA570079 - JP 2018138019-A/142005: Polycomb-Associated Non-Coding RNAs.
MA570080 - JP 2018138019-A/142006: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ACIN1 , ENST00000605057.1, ENST00000605057.2, ENST00000605057.3, ENST00000605057.4, ENST00000605057.5, NM_001386863, S4R3H4, S4R3H4_HUMAN, uc327ith.1, uc327ith.2
UCSC ID: ENST00000605057.6_9
RefSeq Accession: NM_001386863.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.