Human Gene ADPRM (ENST00000379774.5_4) from GENCODE V47lift37

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Description: ADP-ribose/CDP-alcohol diphosphatase, manganese dependent (from RefSeq NM_020233.5)
Gencode Transcript: ENST00000379774.5_4
Gencode Gene: ENSG00000170222.12_7
Transcript (Including UTRs)
Position: hg19 chr17:10,600,911-10,614,875 Size: 13,965 Total Exon Count: 4 Strand: +
Coding Region
Position: hg19 chr17:10,608,244-10,614,461 Size: 6,218 Coding Exon Count: 3

Page Index	Sequence and Links	Primers	CTD	Gene Alleles	RNA-Seq Expression
Microarray Expression	RNA Structure	Other Species	mRNA Descriptions	Other Names	Model Information
Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr17:10,600,911-10,614,875)			mRNA (may differ from genome)		Protein (342 aa)
Gene Sorter	Genome Browser	Other Species FASTA	Gene interactions	Table Schema	AlphaFold
BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards	HGNC
MGI	PubMed	UniProtKB	BioGrid CRISPR DB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D000082 Acetaminophen D003300 Copper D016572 Cyclosporine C558013 NSC 689534 D011794 Quercetin C086401 pentabromodiphenyl ether C517826 tetrabrominated diphenyl ether 47 C025643 vinclozolin

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 11.45 RPKM in Prostate Total median expression: 301.11 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-31.40	91	-0.345	Picture	PostScript	Text
3' UTR	-90.50	414	-0.219	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD	Ensembl

Descriptions from all associated GenBank mRNAs


	BC070155 - Homo sapiens chromosome 17 open reading frame 48, mRNA (cDNA clone MGC:88135 IMAGE:4656998), complete cds. AK292629 - Homo sapiens cDNA FLJ75220 complete cds. AB073393 - Homo sapiens primary neuroblastoma cDNA, clone:Nbla03831, full insert sequence. BC001294 - Homo sapiens chromosome 17 open reading frame 48, mRNA (cDNA clone MGC:5294 IMAGE:3452502), complete cds. AF168715 - Homo sapiens x 006 protein mRNA, complete cds. KF880964 - Homo sapiens manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (ADPRM) mRNA, complete cds. JD167103 - Sequence 148127 from Patent EP1572962. JD348790 - Sequence 329814 from Patent EP1572962. JD259446 - Sequence 240470 from Patent EP1572962. JD419925 - Sequence 400949 from Patent EP1572962. JD252864 - Sequence 233888 from Patent EP1572962. JD279417 - Sequence 260441 from Patent EP1572962. JD499542 - Sequence 480566 from Patent EP1572962. JD167522 - Sequence 148546 from Patent EP1572962. JD183198 - Sequence 164222 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: ADPRM , ENST00000379774.1, ENST00000379774.2, ENST00000379774.3, ENST00000379774.4, NM_020233, uc318pei.1, uc318pei.2, W0NWJ0, W0NWJ0_HUMAN UCSC ID: ENST00000379774.5_4 RefSeq Accession: NM_020233.5

Gene Model Information


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Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.