ID:ANXA4_HUMAN DESCRIPTION: RecName: Full=Annexin A4; AltName: Full=35-beta calcimedin; AltName: Full=Annexin IV; AltName: Full=Annexin-4; AltName: Full=Carbohydrate-binding protein p33/p41; AltName: Full=Chromobindin-4; AltName: Full=Endonexin I; AltName: Full=Lipocortin IV; AltName: Full=P32.5; AltName: Full=PP4-X; AltName: Full=Placental anticoagulant protein II; Short=PAP-II; AltName: Full=Protein II; FUNCTION: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis (By similarity). DOMAIN: A pair of annexin repeats may form one binding site for calcium and phospholipid. MISCELLANEOUS: Seems to bind one calcium ion with high affinity. SIMILARITY: Belongs to the annexin family. SIMILARITY: Contains 4 annexin repeats. SEQUENCE CAUTION: Sequence=AAC41689.1; Type=Erroneous initiation; Sequence=AAH00182.1; Type=Erroneous initiation; Sequence=AAH11659.1; Type=Erroneous initiation; Sequence=BAA11227.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P09525
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.