ID:ACPH_HUMAN DESCRIPTION: RecName: Full=Acylamino-acid-releasing enzyme; Short=AARE; EC=3.4.19.1; AltName: Full=Acyl-peptide hydrolase; Short=APH; AltName: Full=Acylaminoacyl-peptidase; AltName: Full=Oxidized protein hydrolase; Short=OPH; FUNCTION: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. CATALYTIC ACTIVITY: Cleavage of an N-acetyl or N-formyl amino acid from the N-terminus of a polypeptide. SUBUNIT: Homotetramer. SUBCELLULAR LOCATION: Cytoplasm. MASS SPECTROMETRY: Mass=81269.9; Mass_error=8.7; Method=Electrospray; Range=1-732; Source=PubMed:10395453; SIMILARITY: Belongs to the peptidase S9C family. SEQUENCE CAUTION: Sequence=AAA35769.1; Type=Frameshift; Positions=Several;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P13798
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
