ID:RHG09_HUMAN DESCRIPTION: RecName: Full=Rho GTPase-activating protein 9; AltName: Full=Rho-type GTPase-activating protein 9; FUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. SUBUNIT: Interacts with FASLG. TISSUE SPECIFICITY: Predominantly expressed in peripheral blood leukocytes, spleen, and thymus. SIMILARITY: Contains 1 PH domain. SIMILARITY: Contains 1 Rho-GAP domain. SIMILARITY: Contains 1 SH3 domain. SIMILARITY: Contains 1 WW domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9BRR9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007165 signal transduction GO:0043312 neutrophil degranulation GO:0043547 positive regulation of GTPase activity GO:0051056 regulation of small GTPase mediated signal transduction
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
