ID:GDIR2_HUMAN DESCRIPTION: RecName: Full=Rho GDP-dissociation inhibitor 2; Short=Rho GDI 2; AltName: Full=Ly-GDI; AltName: Full=Rho-GDI beta; FUNCTION: Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. SUBCELLULAR LOCATION: Cytoplasm. SIMILARITY: Belongs to the Rho GDI family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P52566
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007162 negative regulation of cell adhesion GO:0007275 multicellular organism development GO:0035023 regulation of Rho protein signal transduction GO:0043547 positive regulation of GTPase activity GO:0050790 regulation of catalytic activity GO:0051056 regulation of small GTPase mediated signal transduction GO:0071461 cellular response to redox state GO:1901164 negative regulation of trophoblast cell migration GO:2000249 regulation of actin cytoskeleton reorganization
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
