Human Gene ARPC1A (ENST00000262942.10_5) from GENCODE V47lift37
  Description: actin related protein 2/3 complex subunit 1A, transcript variant 1 (from RefSeq NM_006409.4)
Gencode Transcript: ENST00000262942.10_5
Gencode Gene: ENSG00000241685.10_8
Transcript (Including UTRs)
   Position: hg19 chr7:98,923,521-98,963,885 Size: 40,365 Total Exon Count: 10 Strand: +
Coding Region
   Position: hg19 chr7:98,930,977-98,963,552 Size: 32,576 Coding Exon Count: 9 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:98,923,521-98,963,885)mRNA (may differ from genome)Protein (370 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: ARPC1A
Diseases sorted by gene-association score: tomato allergy (3), radial neuropathy (2), boomerang dysplasia (2), atelosteogenesis (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 59.49 RPKM in Esophagus - Mucosa
Total median expression: 2019.74 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -40.50136-0.298 Picture PostScript Text
3' UTR -83.00333-0.249 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologGenome BrowserGenome Browser
Gene DetailsGene Details Gene DetailsGene DetailsGene Details
Gene SorterGene Sorter Gene SorterGene SorterGene Sorter
 RGDEnsembl WormBaseSGD
    Protein SequenceProtein Sequence
    AlignmentAlignment

-  Descriptions from all associated GenBank mRNAs
  EU668326 - Homo sapiens epididymis luminal protein 68 (HEL-68) mRNA, complete cds.
AK297111 - Homo sapiens cDNA FLJ57124 complete cds, highly similar to Actin-related protein 2/3 complex subunit 1A.
BC039594 - Homo sapiens actin related protein 2/3 complex, subunit 1A, 41kDa, mRNA (cDNA clone MGC:48820 IMAGE:6018804), complete cds.
BC006445 - Homo sapiens cDNA clone IMAGE:3537492, containing frame-shift errors.
AB209059 - Homo sapiens mRNA for actin related protein 2/3 complex subunit 1A variant protein.
BC047889 - Homo sapiens actin related protein 2/3 complex, subunit 1A, 41kDa, mRNA (cDNA clone MGC:57658 IMAGE:6473050), complete cds.
BC054027 - Homo sapiens actin related protein 2/3 complex, subunit 1A, 41kDa, mRNA (cDNA clone MGC:64823 IMAGE:6514889), complete cds.
Y08999 - H.sapiens mRNA for Sop2p-like protein.
EU832206 - Synthetic construct Homo sapiens clone HAIB:100067235; DKFZo004C0226 actin related protein 2/3 complex, subunit 1A, 41kDa protein (ARPC1A) gene, encodes complete protein.
JF432387 - Synthetic construct Homo sapiens clone IMAGE:100073589 actin related protein 2/3 complex, subunit 1A, 41kDa (ARPC1A) gene, encodes complete protein.
KJ893072 - Synthetic construct Homo sapiens clone ccsbBroadEn_02466 ARPC1A gene, encodes complete protein.
GQ891339 - Homo sapiens clone HEL-S-110d epididymis secretory sperm binding protein mRNA, complete cds.
EU832112 - Synthetic construct Homo sapiens clone HAIB:100067141; DKFZo008C0225 actin related protein 2/3 complex, subunit 1A, 41kDa protein (ARPC1A) gene, encodes complete protein.
AK223015 - Homo sapiens mRNA for actin related protein 2/3 complex subunit 1A variant, clone: HSI13986.
GQ472234 - Homo sapiens epididymis secretory protein Li 307 (HEL-S-307) mRNA, partial cds.
JD415921 - Sequence 396945 from Patent EP1572962.
JD433769 - Sequence 414793 from Patent EP1572962.
CU691736 - Synthetic construct Homo sapiens gateway clone IMAGE:100021107 5' read ARPC1A mRNA.
JD020873 - Sequence 1897 from Patent EP1572962.
JD031794 - Sequence 12818 from Patent EP1572962.
DQ587708 - Homo sapiens piRNA piR-54820, complete sequence.
JD024620 - Sequence 5644 from Patent EP1572962.
JD028191 - Sequence 9215 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000262942.1, ENST00000262942.2, ENST00000262942.3, ENST00000262942.4, ENST00000262942.5, ENST00000262942.6, ENST00000262942.7, ENST00000262942.8, ENST00000262942.9, HEL-68 , NM_006409, uc317hev.1, uc317hev.2, V9HVZ6, V9HVZ6_HUMAN
UCSC ID: ENST00000262942.10_5
RefSeq Accession: NM_006409.4

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.