ID:AT1B3_HUMAN DESCRIPTION: RecName: Full=Sodium/potassium-transporting ATPase subunit beta-3; AltName: Full=Sodium/potassium-dependent ATPase subunit beta-3; Short=ATPB-3; AltName: CD_antigen=CD298; FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. SUBUNIT: Composed of three subunits: alpha (catalytic), beta and gamma. INTERACTION: O75365:PTP4A3; NbExp=1; IntAct=EBI-1054481, EBI-1043866; SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. SIMILARITY: Belongs to the X(+)/potassium ATPases subunit beta family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P54709
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006811 ion transport GO:0006813 potassium ion transport GO:0006814 sodium ion transport GO:0006883 cellular sodium ion homeostasis GO:0010107 potassium ion import GO:0010248 establishment or maintenance of transmembrane electrochemical gradient GO:0030001 metal ion transport GO:0030007 cellular potassium ion homeostasis GO:0032781 positive regulation of ATPase activity GO:0036376 sodium ion export from cell GO:0050821 protein stabilization GO:0050900 leukocyte migration GO:0072659 protein localization to plasma membrane GO:0086009 membrane repolarization GO:1901018 positive regulation of potassium ion transmembrane transporter activity GO:1903278 positive regulation of sodium ion export from cell GO:1903288 positive regulation of potassium ion import
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
