Human Gene AVP (ENST00000380293.3_7) from GENCODE V47lift37
  Description: arginine vasopressin (from RefSeq NM_000490.5)
Gencode Transcript: ENST00000380293.3_7
Gencode Gene: ENSG00000101200.5_9
Transcript (Including UTRs)
   Position: hg19 chr20:3,063,202-3,065,370 Size: 2,169 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg19 chr20:3,063,276-3,065,320 Size: 2,045 Coding Exon Count: 3 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr20:3,063,202-3,065,370)mRNA (may differ from genome)Protein (164 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: AVP
Diseases sorted by gene-association score: diabetes insipidus, neurohypophyseal* (1364), hereditary central diabetes insipidus* (368), diabetes insipidus (86), syndrome of inappropriate antidiuretic hormone (27), inappropriate adh syndrome (20), secondary adrenal insufficiency (18), small cell cancer of the lung, somatic (15), nephrogenic syndrome of inappropriate antidiuresis (13), diabetes insipidus, nephrogenic (12), wolfram syndrome (12), central nervous system organ benign neoplasm (11), myxedema (11), brain germinoma (11), cranial nerve malignant neoplasm (11), impaired renal function disease (9), bronchus cancer (9), space motion sickness (9), paralytic ileus (9), tuberculous epididymitis (8), mixed type thymoma (8), olfactory nerve neoplasm (8), central nervous system germinoma (7), secondary hypertrophic osteoarthropathy (7), haemophilus meningitis (7), benign essential hypertension (7), pituitary hormone deficiency, combined, 2 (7), central nervous system germ cell tumor (6), oculomotor nerve paralysis (6), third cranial nerve disease (6), brain compression (6), pancoast tumor (6), cardiac arrest (5), dental abscess (5), chromophobe adenoma (5), motion sickness (5), sphenoid sinusitis (5), pancreas disease (5), pituitary gland disease (5), superior mesenteric artery syndrome (5), vestibular disease (5), sesame syndrome (4), peripheral vertigo (4), granulomatous angiitis (4), letterer-siwe disease (4), hemopneumothorax (4), analbuminemia (4), carotid artery dissection (4), infant botulism (4), plexopathy (4), premenstrual tension (4), cervix small cell carcinoma (4), granulomatous hepatitis (3), heart disease (3), urinary system disease (2)
* = Manually curated disease association

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 185.85 RPKM in Brain - Hypothalamus
Total median expression: 189.71 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -18.0050-0.360 Picture PostScript Text
3' UTR -22.5074-0.304 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
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 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  M25647 - Human vasopressin mRNA, complete cds.
BC126196 - Homo sapiens arginine vasopressin, mRNA (cDNA clone MGC:161474 IMAGE:8991912), complete cds.
BC018062 - Homo sapiens arginine vasopressin, mRNA (cDNA clone IMAGE:4798442), containing frame-shift errors.
X03172 - Human mRNA for vasopressin precursor.
AF031476 - Homo sapiens vasopressin precursor, mRNA, complete cds.
BC126224 - Homo sapiens arginine vasopressin, mRNA (cDNA clone MGC:161502 IMAGE:8991940), complete cds.
KJ890747 - Synthetic construct Homo sapiens clone ccsbBroadEn_00141 AVP gene, encodes complete protein.
KJ534777 - Homo sapiens clone AVP_iso-B_adult-A04 arginine vasopressin isoform B (AVP) mRNA, partial cds, alternatively spliced.
KJ534778 - Homo sapiens clone AVP_iso-A_adult-A16 arginine vasopressin isoform A (AVP) mRNA, partial cds, alternatively spliced.
AF031475 - Homo sapiens vasopressin-neurophysin precursor, mRNA, partial cds.
JD186797 - Sequence 167821 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AVP , ENST00000380293.1, ENST00000380293.2, hCG_39618 , NM_000490, uc318pmr.1, uc318pmr.2, X5DQP6, X5DQP6_HUMAN
UCSC ID: ENST00000380293.3_7
RefSeq Accession: NM_000490.5

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.