Human Gene B4GALT5 (ENST00000371711.4_7) from GENCODE V47lift37
  Description: beta-1,4-galactosyltransferase 5 (from RefSeq NM_004776.4)
Gencode Transcript: ENST00000371711.4_7
Gencode Gene: ENSG00000158470.5_9
Transcript (Including UTRs)
   Position: hg19 chr20:48,249,482-48,330,415 Size: 80,934 Total Exon Count: 9 Strand: -
Coding Region
   Position: hg19 chr20:48,252,849-48,330,227 Size: 77,379 Coding Exon Count: 9 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr20:48,249,482-48,330,415)mRNA (may differ from genome)Protein (388 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: B4GALT5
Diseases sorted by gene-association score: kidney leiomyosarcoma (4), pharynx cancer (1), vulvitis (1)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 38.39 RPKM in Adrenal Gland
Total median expression: 714.57 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -109.20188-0.581 Picture PostScript Text
3' UTR -1053.703367-0.313 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF02709 - N-terminal domain of galactosyltransferase
PF13733 - N-terminal region of glycosyl transferase group 7

SCOP Domains:
53448 - Nucleotide-diphospho-sugar transferases

ModBase Predicted Comparative 3D Structure on Q7LFU8
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups

Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AK054803 - Homo sapiens cDNA FLJ30241 fis, clone BRACE2002139.
JD446664 - Sequence 427688 from Patent EP1572962.
AF289556 - Homo sapiens clone pp4491 unknown mRNA.
AK056333 - Homo sapiens cDNA FLJ31771 fis, clone NT2RI2007987.
JD563341 - Sequence 544365 from Patent EP1572962.
JD265590 - Sequence 246614 from Patent EP1572962.
JD345187 - Sequence 326211 from Patent EP1572962.
JD512030 - Sequence 493054 from Patent EP1572962.
JD422168 - Sequence 403192 from Patent EP1572962.
JD339006 - Sequence 320030 from Patent EP1572962.
JD403343 - Sequence 384367 from Patent EP1572962.
JD295953 - Sequence 276977 from Patent EP1572962.
JD395699 - Sequence 376723 from Patent EP1572962.
JD392591 - Sequence 373615 from Patent EP1572962.
JD516412 - Sequence 497436 from Patent EP1572962.
JD148913 - Sequence 129937 from Patent EP1572962.
JD390453 - Sequence 371477 from Patent EP1572962.
JD068836 - Sequence 49860 from Patent EP1572962.
JD171296 - Sequence 152320 from Patent EP1572962.
JD061233 - Sequence 42257 from Patent EP1572962.
JD549126 - Sequence 530150 from Patent EP1572962.
JD561508 - Sequence 542532 from Patent EP1572962.
JD092934 - Sequence 73958 from Patent EP1572962.
JD211506 - Sequence 192530 from Patent EP1572962.
JD278312 - Sequence 259336 from Patent EP1572962.
JD312214 - Sequence 293238 from Patent EP1572962.
JD174980 - Sequence 156004 from Patent EP1572962.
JD157779 - Sequence 138803 from Patent EP1572962.
JD228551 - Sequence 209575 from Patent EP1572962.
JD077738 - Sequence 58762 from Patent EP1572962.
JD064055 - Sequence 45079 from Patent EP1572962.
JD441194 - Sequence 422218 from Patent EP1572962.
JD224940 - Sequence 205964 from Patent EP1572962.
JD345428 - Sequence 326452 from Patent EP1572962.
JD552303 - Sequence 533327 from Patent EP1572962.
JD146213 - Sequence 127237 from Patent EP1572962.
JD521086 - Sequence 502110 from Patent EP1572962.
JD212214 - Sequence 193238 from Patent EP1572962.
JD158277 - Sequence 139301 from Patent EP1572962.
JD161687 - Sequence 142711 from Patent EP1572962.
JD153333 - Sequence 134357 from Patent EP1572962.
JD198498 - Sequence 179522 from Patent EP1572962.
JD512577 - Sequence 493601 from Patent EP1572962.
JD335525 - Sequence 316549 from Patent EP1572962.
JD467384 - Sequence 448408 from Patent EP1572962.
JD262991 - Sequence 244015 from Patent EP1572962.
JD469469 - Sequence 450493 from Patent EP1572962.
JD450760 - Sequence 431784 from Patent EP1572962.
AF038663 - Homo sapiens beta-1,4-galactosyltransferase mRNA, complete cds.
JD073625 - Sequence 54649 from Patent EP1572962.
JD303170 - Sequence 284194 from Patent EP1572962.
JD502298 - Sequence 483322 from Patent EP1572962.
AB004550 - Homo sapiens mRNA for beta-1,4-galactosyltransferase (beta-1,4-GalT) V, complete cds.
JD214244 - Sequence 195268 from Patent EP1572962.
JD324722 - Sequence 305746 from Patent EP1572962.
JD287680 - Sequence 268704 from Patent EP1572962.
JD115244 - Sequence 96268 from Patent EP1572962.
JD411527 - Sequence 392551 from Patent EP1572962.
JD200682 - Sequence 181706 from Patent EP1572962.
BC104987 - Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5, mRNA (cDNA clone MGC:132647 IMAGE:8143990), complete cds.
BC112265 - Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5, mRNA (cDNA clone MGC:138470 IMAGE:8327733), complete cds.
JD368013 - Sequence 349037 from Patent EP1572962.
JD201801 - Sequence 182825 from Patent EP1572962.
JD465723 - Sequence 446747 from Patent EP1572962.
JD148155 - Sequence 129179 from Patent EP1572962.
BC074821 - Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5, mRNA (cDNA clone MGC:104086 IMAGE:30915537), complete cds.
BC074873 - Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5, mRNA (cDNA clone MGC:103852 IMAGE:30915234), complete cds.
JD529828 - Sequence 510852 from Patent EP1572962.
HQ258208 - Synthetic construct Homo sapiens clone IMAGE:100072517 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (B4GALT5) gene, encodes complete protein.
KJ892748 - Synthetic construct Homo sapiens clone ccsbBroadEn_02142 B4GALT5 gene, encodes complete protein.
AB527656 - Synthetic construct DNA, clone: pF1KB9394, Homo sapiens B4GALT5 gene for UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5, without stop codon, in Flexi system.
AB871482 - Homo sapiens B4GalT5 mRNA for beta-1,4-galactosyltransferase 5, partial cds.
JD138851 - Sequence 119875 from Patent EP1572962.
MP067507 - Sequence 11 from Patent WO2018232288.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000371711.1, ENST00000371711.2, ENST00000371711.3, gt-V , NM_004776, Q7LFU8, Q7LFU8_HUMAN, uc318jim.1, uc318jim.2
UCSC ID: ENST00000371711.4_7
RefSeq Accession: NM_004776.4
Protein: Q7LFU8

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.