Human Gene BCL2L12 (ENST00000246784.8_10) from GENCODE V47lift37
  Description: BCL2 like 12, transcript variant 1 (from RefSeq NM_138639.2)
Gencode Transcript: ENST00000246784.8_10
Gencode Gene: ENSG00000126453.11_13
Transcript (Including UTRs)
   Position: hg19 chr19:50,169,190-50,177,173 Size: 7,984 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg19 chr19:50,169,950-50,177,005 Size: 7,056 Coding Exon Count: 6 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:50,169,190-50,177,173)mRNA (may differ from genome)Protein (250 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 31.85 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 329.01 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -56.40143-0.394 Picture PostScript Text
3' UTR -26.50168-0.158 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  BC104004 - Homo sapiens BCL2-like 12 (proline rich), mRNA (cDNA clone MGC:120313 IMAGE:40024338), complete cds.
BC104005 - Homo sapiens BCL2-like 12 (proline rich), mRNA (cDNA clone MGC:120314 IMAGE:40024342), complete cds.
BC104006 - Homo sapiens BCL2-like 12 (proline rich), mRNA (cDNA clone MGC:120315 IMAGE:40024345), complete cds.
FJ911908 - Homo sapiens BCL2L12 protein isoform 9 (BCL2L12) mRNA, complete cds, alternatively spliced.
HM347053 - Homo sapiens BCL2L12 protein isoform 7 (BCL2L12) mRNA, complete cds, alternatively spliced.
AB590882 - Synthetic construct DNA, clone: pFN21AE1820, Homo sapiens BCL2L12 gene for BCL2-like 12, without stop codon, in Flexi system.
KJ894885 - Synthetic construct Homo sapiens clone ccsbBroadEn_04279 BCL2L12 gene, encodes complete protein.
FJ868798 - Homo sapiens BCL2L12 protein isoform 4 (BCL2L12) mRNA, complete cds, alternatively spliced.
FJ868799 - Homo sapiens BCL2L12 protein isoform 2 (BCL2L12) mRNA, complete cds, alternatively spliced.
FJ868800 - Homo sapiens BCL2L12 variant 6 (BCL2L12) RNA, complete sequence, alternatively spliced.
FJ868801 - Homo sapiens BCL2L12 variant 7 (BCL2L12) RNA, complete sequence, alternatively spliced.
FJ868802 - Homo sapiens BCL2L12 protein isoform 5 (BCL2L12) mRNA, complete cds, alternatively spliced.
FJ868803 - Homo sapiens BCL2L12 variant 9 (BCL2L12) RNA, complete sequence, alternatively spliced.
FJ911906 - Homo sapiens BCL2L12 protein isoform 6 (BCL2L12) mRNA, complete cds, alternatively spliced.
FJ911907 - Homo sapiens BCL2L12 protein isoform 8 (BCL2L12) mRNA, complete cds, alternatively spliced.
KR820244 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 14 (BCL2L12), complete sequence.
KR820245 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 15 (BCL2L12), complete sequence.
KR820246 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 16 (BCL2L12), complete sequence.
KR820247 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 17 (BCL2L12), complete sequence.
KR820248 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 18 (BCL2L12), complete sequence.
KR820249 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 19 (BCL2L12), complete sequence.
KR820250 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 20 (BCL2L12), complete sequence.
KR820251 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 21 (BCL2L12), complete sequence.
KR820252 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 22 (BCL2L12), complete sequence.
KR820253 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 23 (BCL2L12), complete sequence.
KR820254 - Homo sapiens BCL-2-like protein 12 isoform 10 (BCL2L12) mRNA, complete cds.
KR820255 - Homo sapiens BCL-2-like protein 12 isoform 11 (BCL2L12) mRNA, complete cds.
KR820256 - Homo sapiens BCL-2-like protein 12 isoform 12 (BCL2L12) mRNA, complete cds.
KR820257 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 27 (BCL2L12), complete sequence.
KR820258 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 28 (BCL2L12), complete sequence.
KR820259 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 29 (BCL2L12), complete sequence.
KR820260 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 30 (BCL2L12), complete sequence.
KR820261 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 31 (BCL2L12), complete sequence.
KR820262 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 32 (BCL2L12), complete sequence.
KR820263 - Homo sapiens BCL-2-like protein 12 isoform 13 (BCL2L12) mRNA, complete cds.
KR820264 - Homo sapiens BCL-2-like protein 12 isoform 14 (BCL2L12) mRNA, complete cds.
KR820265 - Homo sapiens BCL-2-like protein 12 isoform 15 (BCL2L12) mRNA, complete cds.
KR820266 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 36 (BCL2L12), complete sequence.
KR820267 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 37 (BCL2L12), complete sequence.
KR820268 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 38 (BCL2L12), complete sequence.
KR820269 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 39 (BCL2L12), complete sequence.
KR820270 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 40 (BCL2L12), complete sequence.
KR820271 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 41 (BCL2L12), complete sequence.
KR820272 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 42 (BCL2L12), complete sequence.
KR820273 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 43 (BCL2L12), complete sequence.
KR820274 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 44 (BCL2L12), complete sequence.
KR820275 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 45 (BCL2L12), complete sequence.
KR820276 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 46 (BCL2L12), complete sequence.
KR820277 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 47 (BCL2L12), complete sequence.
KR820278 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 48 (BCL2L12), complete sequence.
KR820279 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 49 (BCL2L12), complete sequence.
KR820280 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 50 (BCL2L12), complete sequence.
KR820281 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 51 (BCL2L12), complete sequence.
KR820282 - Homo sapiens BCL-2-like protein 12 isoform 16 (BCL2L12) mRNA, complete cds.
KR820283 - Homo sapiens BCL-2-like protein 12 isoform 17 (BCL2L12) mRNA, complete cds.
KR820284 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 54 (BCL2L12), complete sequence.
KR820285 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 55 (BCL2L12), complete sequence.
KR820286 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 56 (BCL2L12), complete sequence.
KR820287 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 57 (BCL2L12), complete sequence.
KR820288 - Homo sapiens BCL-2-like protein 12 isoform 18 (BCL2L12) mRNA, complete cds.
KR820289 - Homo sapiens BCL-2-like protein 12 isoform 19 (BCL2L12) mRNA, complete cds.
KR820290 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 60 (BCL2L12), complete sequence.
KR820291 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 61 (BCL2L12), complete sequence.
KR820292 - Homo sapiens BCL2-like 12 (proline rich), transcript variant 62 (BCL2L12), complete sequence.
KR820293 - Homo sapiens BCL-2-like protein 12 isoform 20 (BCL2L12) mRNA, complete cds.
BC007724 - Homo sapiens BCL2-like 12 (proline rich), mRNA (cDNA clone IMAGE:4302950), partial cds.
KJ903350 - Synthetic construct Homo sapiens clone ccsbBroadEn_12744 BCL2L12 gene, encodes complete protein.
JD398184 - Sequence 379208 from Patent EP1572962.
JD540712 - Sequence 521736 from Patent EP1572962.
JD444695 - Sequence 425719 from Patent EP1572962.
JD401090 - Sequence 382114 from Patent EP1572962.
JD401096 - Sequence 382120 from Patent EP1572962.
JD116642 - Sequence 97666 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A087WSV0, A0A087WSV0_HUMAN, BCL2L12 , ENST00000246784.1, ENST00000246784.2, ENST00000246784.3, ENST00000246784.4, ENST00000246784.5, ENST00000246784.6, ENST00000246784.7, NM_138639, uc317eud.1, uc317eud.2
UCSC ID: ENST00000246784.8_10
RefSeq Accession: NM_138639.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.