ID:BMS1_HUMAN DESCRIPTION: RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog; FUNCTION: May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity). SUBCELLULAR LOCATION: Nucleus, nucleolus (By similarity). SIMILARITY: Belongs to the BMS1/TSR1 family. BMS1 subfamily. SEQUENCE CAUTION: Sequence=BAA11504.2; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q14692
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK308420 - Homo sapiens cDNA, FLJ98368. BC043345 - Homo sapiens BMS1 homolog, ribosome assembly protein (yeast), mRNA (cDNA clone MGC:49890 IMAGE:6062924), complete cds. D80009 - Homo sapiens KIAA0187 mRNA. BC150252 - Homo sapiens BMS1 homolog, ribosome assembly protein (yeast), mRNA (cDNA clone MGC:166808 IMAGE:9007274), complete cds. KJ898093 - Synthetic construct Homo sapiens clone ccsbBroadEn_07487 BMS1 gene, encodes complete protein. AB385294 - Synthetic construct DNA, clone: pF1KA0187, Homo sapiens BMS1 gene for ribosome biogenesis protein BMS1 homolog, complete cds, without stop codon, in Flexi system. DQ592769 - Homo sapiens piRNA piR-59881, complete sequence. JD465092 - Sequence 446116 from Patent EP1572962. JD221509 - Sequence 202533 from Patent EP1572962. JD565471 - Sequence 546495 from Patent EP1572962. JD182428 - Sequence 163452 from Patent EP1572962. JD498063 - Sequence 479087 from Patent EP1572962. JD080486 - Sequence 61510 from Patent EP1572962. JD527024 - Sequence 508048 from Patent EP1572962. JD518459 - Sequence 499483 from Patent EP1572962. JD182371 - Sequence 163395 from Patent EP1572962. JD036765 - Sequence 17789 from Patent EP1572962. JD036764 - Sequence 17788 from Patent EP1572962. JD320124 - Sequence 301148 from Patent EP1572962. JD077545 - Sequence 58569 from Patent EP1572962. JD492803 - Sequence 473827 from Patent EP1572962. JD183038 - Sequence 164062 from Patent EP1572962. JD193786 - Sequence 174810 from Patent EP1572962. JD436974 - Sequence 417998 from Patent EP1572962. JD278505 - Sequence 259529 from Patent EP1572962. JD290430 - Sequence 271454 from Patent EP1572962. JD528400 - Sequence 509424 from Patent EP1572962. JD286350 - Sequence 267374 from Patent EP1572962. JD225881 - Sequence 206905 from Patent EP1572962. JD377614 - Sequence 358638 from Patent EP1572962. JD028287 - Sequence 9311 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q14692 (Reactome details) participates in the following event(s):
R-HSA-6790906 EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6790901 rRNA modification in the nucleus and cytosol R-HSA-8868773 rRNA processing in the nucleus and cytosol R-HSA-72312 rRNA processing R-HSA-8953854 Metabolism of RNA