ID:BRI3B_HUMAN DESCRIPTION: RecName: Full=BRI3-binding protein; Short=I3-binding protein; AltName: Full=Cervical cancer 1 proto-oncogene-binding protein KG19; AltName: Full=HCCRBP-1; FUNCTION: Involved in tumorigenesis and may function by stabilizing p53/TP53. SUBUNIT: Interacts with LETMD1. SUBCELLULAR LOCATION: Mitochondrion outer membrane; Multi-pass membrane protein (Probable). TISSUE SPECIFICITY: Most abundantly expressed in brain, liver and kidney. Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas. SEQUENCE CAUTION: Sequence=AAL33003.2; Type=Frameshift; Positions=43, 47, 59;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF14965 - Negative regulator of p53/TP53
ModBase Predicted Comparative 3D Structure on Q8WY22
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
