ID:E9PF82_HUMAN DESCRIPTION: SubName: Full=Calcium/calmodulin-dependent protein kinase type II subunit delta; SIMILARITY: Contains 1 protein kinase domain. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00069 - Protein kinase domain PF07714 - Protein tyrosine and serine/threonine kinase PF08332 - Calcium/calmodulin dependent protein kinase II association domain PF13474 - SnoaL-like domain PF14534 - Domain of unknown function (DUF4440)
ModBase Predicted Comparative 3D Structure on E9PF82
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0001666 response to hypoxia GO:0006468 protein phosphorylation GO:0010389 regulation of G2/M transition of mitotic cell cycle GO:0010649 regulation of cell communication by electrical coupling GO:0010666 positive regulation of cardiac muscle cell apoptotic process GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014911 positive regulation of smooth muscle cell migration GO:0018105 peptidyl-serine phosphorylation GO:0018107 peptidyl-threonine phosphorylation GO:0030007 cellular potassium ion homeostasis GO:0032469 endoplasmic reticulum calcium ion homeostasis GO:0035022 positive regulation of Rac protein signal transduction GO:0046777 protein autophosphorylation GO:0048661 positive regulation of smooth muscle cell proliferation GO:0055119 relaxation of cardiac muscle GO:0061049 cell growth involved in cardiac muscle cell development GO:0070374 positive regulation of ERK1 and ERK2 cascade GO:0086003 cardiac muscle cell contraction GO:0098901 regulation of cardiac muscle cell action potential GO:1901897 regulation of relaxation of cardiac muscle GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel GO:1903076 regulation of protein localization to plasma membrane