ID:CAN13_HUMAN DESCRIPTION: RecName: Full=Calpain-13; EC=3.4.22.-; AltName: Full=Calcium-activated neutral proteinase 13; Short=CANP 13; FUNCTION: Probable non-lysosomal thiol-protease (By similarity). TISSUE SPECIFICITY: Weakly expressed in lung and testis. Weakly or not expressed in other tissues. SIMILARITY: Belongs to the peptidase C2 family. SIMILARITY: Contains 1 calpain catalytic domain. SIMILARITY: Contains 2 EF-hand domains. CAUTION: It is unlikely that this protein binds calcium as none of the 2 EF-hand domains seem to contain a canonical calcium-binding site.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6MZZ7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.