Human Gene CCT5 (ENST00000280326.9_4) from GENCODE V47lift37
  Description: chaperonin containing TCP1 subunit 5, transcript variant 1 (from RefSeq NM_012073.5)
Gencode Transcript: ENST00000280326.9_4
Gencode Gene: ENSG00000150753.12_12
Transcript (Including UTRs)
   Position: hg19 chr5:10,250,392-10,266,501 Size: 16,110 Total Exon Count: 11 Strand: +
Coding Region
   Position: hg19 chr5:10,250,453-10,264,895 Size: 14,443 Coding Exon Count: 11 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:10,250,392-10,266,501)mRNA (may differ from genome)Protein (541 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: CCT5
Diseases sorted by gene-association score: neuropathy, hereditary sensory, with spastic paraplegia* (1180), autosomal recessive sensory neuropathy with spastic paraplegia* (100), neuropathy (11), epididymo-orchitis (9), insensitivity to pain, congenital (4), benign epilepsy with centrotemporal spikes (4)
* = Manually curated disease association

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • D004997 Ethinyl Estradiol
  • D006861 Hydrogen Peroxide
  • D013749 Tetrachlorodibenzodioxin
  • C576882 1-(2-trifluoromethoxyphenyl)-2-nitroethanone
  • C029790 2,2',3',4,4',5-hexachlorobiphenyl
  • C016403 2,4-dinitrotoluene
  • C023514 2,6-dinitrotoluene
  • C049584 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
  • D015127 9,10-Dimethyl-1,2-benzanthracene
  • D000117 Acetylglucosamine
          more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 65.41 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 1275.91 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -18.3061-0.300 Picture PostScript Text
3' UTR -452.601606-0.282 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologGenome Browser
Gene DetailsGene Details Gene Details Gene Details
Gene SorterGene Sorter Gene Sorter Gene Sorter
 RGDEnsembl  SGD
     Protein Sequence
     Alignment

-  Descriptions from all associated GenBank mRNAs
  AK301760 - Homo sapiens cDNA FLJ58784 complete cds, highly similar to T-complex protein 1 subunit epsilon.
FJ224303 - Homo sapiens epididymis secretory protein Li 69 (HEL-S-69) mRNA, complete cds.
LF385033 - JP 2014500723-A/192536: Polycomb-Associated Non-Coding RNAs.
AK302368 - Homo sapiens cDNA FLJ52361 complete cds, highly similar to T-complex protein 1 subunit epsilon.
BC035499 - Homo sapiens chaperonin containing TCP1, subunit 5 (epsilon), mRNA (cDNA clone MGC:20797 IMAGE:4329194), complete cds.
AK290393 - Homo sapiens cDNA FLJ78433 complete cds, highly similar to Homo sapiens chaperonin containing TCP1, subunit 5 (epsilon) (CCT5), mRNA.
AK301985 - Homo sapiens cDNA FLJ54333 complete cds, highly similar to T-complex protein 1 subunit epsilon.
BC040027 - Homo sapiens chaperonin containing TCP1, subunit 5 (epsilon), mRNA (cDNA clone IMAGE:5394937).
AK303086 - Homo sapiens cDNA FLJ53116 complete cds, highly similar to T-complex protein 1 subunit epsilon.
D43950 - Homo sapiens KIAA0098 mRNA for KIAA0098 protein.
BC006543 - Homo sapiens chaperonin containing TCP1, subunit 5 (epsilon), mRNA (cDNA clone MGC:2389 IMAGE:2824199), complete cds.
AK293437 - Homo sapiens cDNA FLJ51711 complete cds, highly similar to T-complex protein 1 subunit epsilon.
AK303147 - Homo sapiens cDNA FLJ59103 complete cds, highly similar to T-complex protein 1 subunit epsilon.
AK289353 - Homo sapiens cDNA FLJ75559 complete cds, highly similar to Homo sapiens chaperonin containing TCP1, subunit 5 (epsilon) (CCT5), mRNA.
DQ892743 - Synthetic construct clone IMAGE:100005373; FLH189289.01X; RZPDo839D0774D chaperonin containing TCP1, subunit 5 (epsilon) (CCT5) gene, encodes complete protein.
DQ895989 - Synthetic construct Homo sapiens clone IMAGE:100010449; FLH189285.01L; RZPDo839D0764D chaperonin containing TCP1, subunit 5 (epsilon) (CCT5) gene, encodes complete protein.
AB383748 - Synthetic construct DNA, clone: pF1KSDA0098, Homo sapiens CCT5 gene for T-complex protein 1 subunit epsilon, complete cds, without stop codon, in Flexi system.
KJ898427 - Synthetic construct Homo sapiens clone ccsbBroadEn_07821 CCT5 gene, encodes complete protein.
KR710230 - Synthetic construct Homo sapiens clone CCSBHm_00010693 CCT5 (CCT5) mRNA, encodes complete protein.
BC002971 - Homo sapiens, clone IMAGE:3543711, mRNA, partial cds.
LF336094 - JP 2014500723-A/143597: Polycomb-Associated Non-Coding RNAs.
AK302383 - Homo sapiens cDNA FLJ52362 complete cds, highly similar to T-complex protein 1 subunit epsilon.
AK293341 - Homo sapiens cDNA FLJ50442 complete cds, highly similar to T-complex protein 1 subunit epsilon.
AK316376 - Homo sapiens cDNA, FLJ79275 complete cds, highly similar to T-complex protein 1 subunit epsilon.
LF336092 - JP 2014500723-A/143595: Polycomb-Associated Non-Coding RNAs.
LF336091 - JP 2014500723-A/143594: Polycomb-Associated Non-Coding RNAs.
LF336090 - JP 2014500723-A/143593: Polycomb-Associated Non-Coding RNAs.
LF336089 - JP 2014500723-A/143592: Polycomb-Associated Non-Coding RNAs.
BC009454 - Homo sapiens, clone IMAGE:3534054, mRNA, partial cds.
LF336088 - JP 2014500723-A/143591: Polycomb-Associated Non-Coding RNAs.
LF336087 - JP 2014500723-A/143590: Polycomb-Associated Non-Coding RNAs.
DQ591408 - Homo sapiens piRNA piR-58520, complete sequence.
LF336086 - JP 2014500723-A/143589: Polycomb-Associated Non-Coding RNAs.
LF336085 - JP 2014500723-A/143588: Polycomb-Associated Non-Coding RNAs.
AF275798 - Homo sapiens PNAS-102 mRNA, complete cds.
LF336083 - JP 2014500723-A/143586: Polycomb-Associated Non-Coding RNAs.
LF336082 - JP 2014500723-A/143585: Polycomb-Associated Non-Coding RNAs.
DL491562 - Novel nucleic acids.
DL490164 - Novel nucleic acids.
AJ012489 - Homo sapiens mRNA activated in tumor suppression, clone TSAP9.
LF336081 - JP 2014500723-A/143584: Polycomb-Associated Non-Coding RNAs.
JD260064 - Sequence 241088 from Patent EP1572962.
JD450131 - Sequence 431155 from Patent EP1572962.
LF336080 - JP 2014500723-A/143583: Polycomb-Associated Non-Coding RNAs.
MA620610 - JP 2018138019-A/192536: Polycomb-Associated Non-Coding RNAs.
MA571671 - JP 2018138019-A/143597: Polycomb-Associated Non-Coding RNAs.
MA571669 - JP 2018138019-A/143595: Polycomb-Associated Non-Coding RNAs.
MA571668 - JP 2018138019-A/143594: Polycomb-Associated Non-Coding RNAs.
MA571667 - JP 2018138019-A/143593: Polycomb-Associated Non-Coding RNAs.
MA571666 - JP 2018138019-A/143592: Polycomb-Associated Non-Coding RNAs.
MA571665 - JP 2018138019-A/143591: Polycomb-Associated Non-Coding RNAs.
MA571664 - JP 2018138019-A/143590: Polycomb-Associated Non-Coding RNAs.
MA571663 - JP 2018138019-A/143589: Polycomb-Associated Non-Coding RNAs.
MA571662 - JP 2018138019-A/143588: Polycomb-Associated Non-Coding RNAs.
MA571660 - JP 2018138019-A/143586: Polycomb-Associated Non-Coding RNAs.
MA571659 - JP 2018138019-A/143585: Polycomb-Associated Non-Coding RNAs.
MA571658 - JP 2018138019-A/143584: Polycomb-Associated Non-Coding RNAs.
MA571657 - JP 2018138019-A/143583: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000280326.1, ENST00000280326.2, ENST00000280326.3, ENST00000280326.4, ENST00000280326.5, ENST00000280326.6, ENST00000280326.7, ENST00000280326.8, HEL-S-69 , NM_012073, uc317jtl.1, uc317jtl.2, V9HW37, V9HW37_HUMAN
UCSC ID: ENST00000280326.9_4
RefSeq Accession: NM_012073.5

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.