Human Gene CDH10 (ENST00000264463.8_7) from GENCODE V47lift37
  Description: cadherin 10, transcript variant 1 (from RefSeq NM_006727.5)
Gencode Transcript: ENST00000264463.8_7
Gencode Gene: ENSG00000040731.10_10
Transcript (Including UTRs)
   Position: hg19 chr5:24,487,209-24,645,087 Size: 157,879 Total Exon Count: 12 Strand: -
Coding Region
   Position: hg19 chr5:24,487,772-24,593,599 Size: 105,828 Coding Exon Count: 11 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:24,487,209-24,645,087)mRNA (may differ from genome)Protein (788 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: CDH10
Diseases sorted by gene-association score: lung squamous cell carcinoma (19)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 16.08 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 86.55 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -129.70508-0.255 Picture PostScript Text
3' UTR -101.50563-0.180 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  AF039747 - Homo sapiens cadherin-10 (CDH10) mRNA, complete cds.
AB035303 - Homo sapiens CDH10 mRNA for cadherin-10, complete cds.
BC144168 - Homo sapiens cDNA clone IMAGE:9052688.
BC156818 - Synthetic construct Homo sapiens clone IMAGE:100062584, MGC:190574 cadherin 10, type 2 (T2-cadherin) (CDH10) mRNA, encodes complete protein.
KJ534806 - Homo sapiens clone CDH10_iso-B_fetal-F01 cadherin 10 type 2 isoform B (CDH10) mRNA, partial cds, alternatively spliced.
KJ534807 - Homo sapiens clone CDH10_iso-C_fetal-F08 cadherin 10 type 2 isoform C (CDH10) mRNA, partial cds, alternatively spliced.
KJ534808 - Homo sapiens clone CDH10_iso-A_fetal-F16 cadherin 10 type 2 isoform A (CDH10) mRNA, partial cds, alternatively spliced.
BC152828 - Synthetic construct Homo sapiens clone IMAGE:100016083, MGC:184164 cadherin 10, type 2 (T2-cadherin) (CDH10) mRNA, encodes complete protein.
JD500732 - Sequence 481756 from Patent EP1572962.
JD514844 - Sequence 495868 from Patent EP1572962.
JD381789 - Sequence 362813 from Patent EP1572962.
JD516688 - Sequence 497712 from Patent EP1572962.
JD054211 - Sequence 35235 from Patent EP1572962.
JD281263 - Sequence 262287 from Patent EP1572962.
JD490578 - Sequence 471602 from Patent EP1572962.
JD359889 - Sequence 340913 from Patent EP1572962.
JD483783 - Sequence 464807 from Patent EP1572962.
JD431305 - Sequence 412329 from Patent EP1572962.
JD114391 - Sequence 95415 from Patent EP1572962.
JD188968 - Sequence 169992 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: CDH10 , ENST00000264463.1, ENST00000264463.2, ENST00000264463.3, ENST00000264463.4, ENST00000264463.5, ENST00000264463.6, ENST00000264463.7, hCG_36812 , NM_006727, uc317hst.1, uc317hst.2, X5D8X5, X5D8X5_HUMAN
UCSC ID: ENST00000264463.8_7
RefSeq Accession: NM_006727.5

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.