Human Gene CEP95 (ENST00000553956.6_1) from GENCODE V47lift37
  Description: centrosomal protein 95 (from HGNC CEP95)
Gencode Transcript: ENST00000553956.6_1
Gencode Gene: ENSG00000258890.8_18
Transcript (Including UTRs)
   Position: hg19 chr17:62,503,203-62,534,064 Size: 30,862 Total Exon Count: 20 Strand: +
Coding Region
   Position: hg19 chr17:62,503,216-62,510,390 Size: 7,175 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:62,503,203-62,534,064)mRNA (may differ from genome)Protein (99 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsHGNC
MGIPubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: H0YJW6_HUMAN
DESCRIPTION: SubName: Full=Centrosomal protein of 95 kDa;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 22.91 RPKM in Ovary
Total median expression: 554.46 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -586.102356-0.249 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026619 - CEP95

Pfam Domains:
PF19016 - Domain of unknown function (DUF5745)

ModBase Predicted Comparative 3D Structure on H0YJW6
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
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-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0000922 spindle pole
GO:0005813 centrosome


-  Descriptions from all associated GenBank mRNAs
  AK057326 - Homo sapiens cDNA FLJ32764 fis, clone TESTI2001829.
AK316257 - Homo sapiens cDNA, FLJ79156 complete cds, highly similar to Coiled-coil domain-containing protein 45.
AK290587 - Homo sapiens cDNA FLJ76049 complete cds.
AK297409 - Homo sapiens cDNA FLJ54025 complete cds, highly similar to Coiled-coil domain-containing protein 45.
BC009518 - Homo sapiens coiled-coil domain containing 45, mRNA (cDNA clone MGC:10965 IMAGE:3633884), complete cds.
AL832822 - Homo sapiens mRNA; cDNA DKFZp667E1824 (from clone DKFZp667E1824).
KJ895136 - Synthetic construct Homo sapiens clone ccsbBroadEn_04530 CEP95 gene, encodes complete protein.
AF130069 - Homo sapiens clone FLB8436 PRO2277 mRNA, complete cds.
BX641136 - Homo sapiens mRNA; cDNA DKFZp686H24132 (from clone DKFZp686H24132).
BC029461 - Homo sapiens coiled-coil domain containing 45, mRNA (cDNA clone IMAGE:4663179), with apparent retained intron.
JD472060 - Sequence 453084 from Patent EP1572962.
JD201980 - Sequence 183004 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AL832822, CEP95 , ENST00000553956.1, ENST00000553956.2, ENST00000553956.3, ENST00000553956.4, ENST00000553956.5, H0YJW6, H0YJW6_HUMAN, uc325ffk.1
UCSC ID: ENST00000553956.6_1
RefSeq Accession: NR_133644.2
Protein: H0YJW6

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.