The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P26441
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007165 signal transduction GO:0007275 multicellular organism development GO:0007399 nervous system development GO:0008284 positive regulation of cell proliferation GO:0010469 regulation of receptor activity GO:0010628 positive regulation of gene expression GO:0019221 cytokine-mediated signaling pathway GO:0030154 cell differentiation GO:0040007 growth GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein GO:0043524 negative regulation of neuron apoptotic process GO:0046533 negative regulation of photoreceptor cell differentiation GO:0046668 regulation of retinal cell programmed cell death GO:0048143 astrocyte activation GO:0048644 muscle organ morphogenesis GO:0048666 neuron development GO:0048680 positive regulation of axon regeneration GO:0070120 ciliary neurotrophic factor-mediated signaling pathway