Human Gene CXCL14 (ENST00000512158.6_10) from GENCODE V47lift37
  Description: C-X-C motif chemokine ligand 14 (from RefSeq NM_004887.5)
Gencode Transcript: ENST00000512158.6_10
Gencode Gene: ENSG00000145824.13_13
Transcript (Including UTRs)
   Position: hg19 chr5:134,906,369-134,914,681 Size: 8,313 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chr5:134,907,543-134,914,468 Size: 6,926 Coding Exon Count: 4 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:134,906,369-134,914,681)mRNA (may differ from genome)Protein (99 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCHuman Cortex Gene ExpressionMalacardsMGIOMIMPubMed
UniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: CXCL14
Diseases sorted by gene-association score: squamous cell carcinoma, head and neck (3), pelvic lipomatosis (2), otomycosis (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 475.38 RPKM in Skin - Sun Exposed (Lower leg)
Total median expression: 2562.36 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -91.80213-0.431 Picture PostScript Text
3' UTR -300.801174-0.256 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  AY358906 - Homo sapiens clone DNA39523 SCYB14 (UNQ240) mRNA, complete cds.
AF144103 - Homo sapiens NJAC protein (NJAC) mRNA, complete cds.
AK075514 - Homo sapiens cDNA PSEC0212 fis, clone HEMBA1003764, highly similar to Homo sapiens chemokine (C-X-C motif) ligand 14 (CXCL14), mRNA.
JD038625 - Sequence 19649 from Patent EP1572962.
JD041908 - Sequence 22932 from Patent EP1572962.
JD309865 - Sequence 290889 from Patent EP1572962.
JD260363 - Sequence 241387 from Patent EP1572962.
JD467882 - Sequence 448906 from Patent EP1572962.
JD473491 - Sequence 454515 from Patent EP1572962.
JD399310 - Sequence 380334 from Patent EP1572962.
JD330395 - Sequence 311419 from Patent EP1572962.
JD439494 - Sequence 420518 from Patent EP1572962.
JD342597 - Sequence 323621 from Patent EP1572962.
AF086340 - Homo sapiens full length insert cDNA clone ZD60C06.
AF073957 - Homo sapiens CXC chemokine BRAK mRNA, complete cds.
AF106911 - Homo sapiens chemokine MIP-2 gamma (MIP-2 gamma) mRNA, complete cds.
BC003513 - Homo sapiens chemokine (C-X-C motif) ligand 14, mRNA (cDNA clone MGC:10687 IMAGE:3611714), complete cds.
AK056613 - Homo sapiens cDNA FLJ32051 fis, clone NTONG2001428.
JD301798 - Sequence 282822 from Patent EP1572962.
BT007080 - Homo sapiens chemokine (C-X-C motif) ligand 14 mRNA, complete cds.
KJ892800 - Synthetic construct Homo sapiens clone ccsbBroadEn_02194 CXCL14 gene, encodes complete protein.
AB528117 - Synthetic construct DNA, clone: pF1KE0215, Homo sapiens CXCL14 gene for chemokine (C-X-C motif) ligand 14, without stop codon, in Flexi system.
AM392840 - Synthetic construct Homo sapiens clone IMAGE:100002584 for hypothetical protein (CXCL14 gene).
AB543622 - Homo sapiens CXCL14 mRNA for tumor-suppressing chemokine, partial cds.
JD474298 - Sequence 455322 from Patent EP1572962.
JD390097 - Sequence 371121 from Patent EP1572962.
JD483125 - Sequence 464149 from Patent EP1572962.
JD137812 - Sequence 118836 from Patent EP1572962.
JD139912 - Sequence 120936 from Patent EP1572962.
JD049650 - Sequence 30674 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A0C4DGC1, A0A0C4DGC1_HUMAN, CXCL14 , ENST00000512158.1, ENST00000512158.2, ENST00000512158.3, ENST00000512158.4, ENST00000512158.5, NM_004887, uc323ioa.1, uc323ioa.2
UCSC ID: ENST00000512158.6_10
RefSeq Accession: NM_004887.5

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.