Human Gene DDX46 (ENST00000452510.7_9) from GENCODE V47lift37
  Description: DEAD-box helicase 46, transcript variant 1 (from RefSeq NM_001300860.2)
Gencode Transcript: ENST00000452510.7_9
Gencode Gene: ENSG00000145833.16_12
Transcript (Including UTRs)
   Position: hg19 chr5:134,094,469-134,166,811 Size: 72,343 Total Exon Count: 23 Strand: +
Coding Region
   Position: hg19 chr5:134,094,629-134,164,396 Size: 69,768 Coding Exon Count: 23 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:134,094,469-134,166,811)mRNA (may differ from genome)Protein (1032 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 19.61 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 532.67 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -64.30160-0.402 Picture PostScript Text
3' UTR -545.502415-0.226 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details Gene DetailsGene Details 
Gene SorterGene Sorter Gene SorterGene Sorter 
 RGD  WormBase 
      
      

-  Descriptions from all associated GenBank mRNAs
  AK126011 - Homo sapiens cDNA FLJ44023 fis, clone TESTI4026510, highly similar to Homo sapiens RNA helicase.
BC105598 - Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, mRNA (cDNA clone IMAGE:4714593), partial cds.
AK291788 - Homo sapiens cDNA FLJ78679 complete cds, highly similar to Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 (DDX46), mRNA.
AF106680 - Homo sapiens RNA helicase mRNA, complete cds.
AB018344 - Homo sapiens KIAA0801 mRNA for KIAA0801 protein.
BC012304 - Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, mRNA (cDNA clone MGC:9936 IMAGE:3873814), complete cds.
JD514166 - Sequence 495190 from Patent EP1572962.
CU680282 - Synthetic construct Homo sapiens gateway clone IMAGE:100020513 5' read DDX46 mRNA.
BX647426 - Homo sapiens mRNA; cDNA DKFZp686J23144 (from clone DKFZp686J23144).
AK058058 - Homo sapiens cDNA FLJ25329 fis, clone TST00542.
JD146756 - Sequence 127780 from Patent EP1572962.
JD490645 - Sequence 471669 from Patent EP1572962.
JD431377 - Sequence 412401 from Patent EP1572962.
JD286873 - Sequence 267897 from Patent EP1572962.
JD286874 - Sequence 267898 from Patent EP1572962.
JD511652 - Sequence 492676 from Patent EP1572962.
BC030755 - Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, mRNA (cDNA clone IMAGE:4797178).
JD020421 - Sequence 1445 from Patent EP1572962.
JD035572 - Sequence 16596 from Patent EP1572962.
JD035395 - Sequence 16419 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A0C4DG89, A0A0C4DG89_HUMAN, DDX46 , ENST00000452510.1, ENST00000452510.2, ENST00000452510.3, ENST00000452510.4, ENST00000452510.5, ENST00000452510.6, NM_001300860, uc320tuh.1, uc320tuh.2
UCSC ID: ENST00000452510.7_9
RefSeq Accession: NM_001300860.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.