Human Gene DENND1A (ENST00000394215.7_7) from GENCODE V47lift37
  Description: DENN domain containing 1A, transcript variant 11 (from RefSeq NM_001400449.1)
Gencode Transcript: ENST00000394215.7_7
Gencode Gene: ENSG00000119522.18_16
Transcript (Including UTRs)
   Position: hg19 chr9:126,141,937-126,692,405 Size: 550,469 Total Exon Count: 24 Strand: -
Coding Region
   Position: hg19 chr9:126,143,711-126,692,184 Size: 548,474 Coding Exon Count: 24 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:126,141,937-126,692,405)mRNA (may differ from genome)Protein (1070 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsHGNC
MGIPubMedUniProtKBWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.60 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 95.94 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -108.40221-0.490 Picture PostScript Text
3' UTR -726.301774-0.409 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  KJ894450 - Synthetic construct Homo sapiens clone ccsbBroadEn_03844 DENND1A gene, encodes complete protein.
AK074151 - Homo sapiens mRNA for FLJ00224 protein.
AB046828 - Homo sapiens mRNA for KIAA1608 protein, partial cds.
AK299867 - Homo sapiens cDNA FLJ50200 complete cds, highly similar to DENN domain-containing protein 1A.
AK295710 - Homo sapiens cDNA FLJ50169 complete cds, highly similar to DENN domain-containing protein 1A.
BC009616 - Homo sapiens DENN/MADD domain containing 1A, mRNA (cDNA clone IMAGE:3905823), partial cds.
BC039703 - Homo sapiens DENN/MADD domain containing 1A, mRNA (cDNA clone MGC:47574 IMAGE:4999484), complete cds.
AK024782 - Homo sapiens cDNA: FLJ21129 fis, clone CAS06266.
AK225104 - Homo sapiens mRNA for hypothetical protein LOC57706 isoform 2 variant, clone: CAS06266.
JF432807 - Synthetic construct Homo sapiens clone IMAGE:100074125 DENN/MADD domain containing 1A (DENND1A) gene, encodes complete protein.
BC028061 - Homo sapiens DENN/MADD domain containing 1A, mRNA (cDNA clone IMAGE:5188276), partial cds.
CU691746 - Synthetic construct Homo sapiens gateway clone IMAGE:100019871 5' read DENND1A mRNA.
DQ580919 - Homo sapiens piRNA piR-49031, complete sequence.
LF205681 - JP 2014500723-A/13184: Polycomb-Associated Non-Coding RNAs.
LF347083 - JP 2014500723-A/154586: Polycomb-Associated Non-Coding RNAs.
AK310661 - Homo sapiens cDNA, FLJ17703.
LF347084 - JP 2014500723-A/154587: Polycomb-Associated Non-Coding RNAs.
LF347085 - JP 2014500723-A/154588: Polycomb-Associated Non-Coding RNAs.
MA582660 - JP 2018138019-A/154586: Polycomb-Associated Non-Coding RNAs.
MA582661 - JP 2018138019-A/154587: Polycomb-Associated Non-Coding RNAs.
MA582662 - JP 2018138019-A/154588: Polycomb-Associated Non-Coding RNAs.
MA441258 - JP 2018138019-A/13184: Polycomb-Associated Non-Coding RNAs.
JD462970 - Sequence 443994 from Patent EP1572962.
JD211419 - Sequence 192443 from Patent EP1572962.
JD469194 - Sequence 450218 from Patent EP1572962.
JD421752 - Sequence 402776 from Patent EP1572962.
JD193689 - Sequence 174713 from Patent EP1572962.
JD387628 - Sequence 368652 from Patent EP1572962.
JD054924 - Sequence 35948 from Patent EP1572962.
JD355659 - Sequence 336683 from Patent EP1572962.
JD111772 - Sequence 92796 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A0A0MS48, A0A0A0MS48_HUMAN, DENND1A , ENST00000394215.1, ENST00000394215.2, ENST00000394215.3, ENST00000394215.4, ENST00000394215.5, ENST00000394215.6, NM_001400449, uc318wmd.1, uc318wmd.2
UCSC ID: ENST00000394215.7_7
RefSeq Accession: NM_001352964.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.