Human Gene DNAJB1 (ENST00000254322.3_7) from GENCODE V47lift37
Description: DnaJ heat shock protein family (Hsp40) member B1, transcript variant 1 (from RefSeq NM_006145.3)
Gencode Transcript: ENST00000254322.3_7
Gencode Gene: ENSG00000132002.10_13
Transcript (Including UTRs)
Position: hg19 chr19:14,625,581-14,629,209 Size: 3,629 Total Exon Count: 3 Strand: -
Coding Region
Position: hg19 chr19:14,626,752-14,629,161 Size: 2,410 Coding Exon Count: 3
Data last updated at UCSC: 2024-08-22 23:36:26
Sequence and Links to Tools and Databases
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR002939 - DnaJ_C
IPR001623 - DnaJ_N
IPR018253 - Heat_shock_DnaJ_CS
IPR008971 - HSP40/DnaJ_pept-bd
IPR003095 - Hsp_DnaJ
Pfam Domains: PF00226 - DnaJ domain
PF01556 - DnaJ C terminal domain
SCOP Domains: 46565 - Chaperone J-domain
49493 - HSP40/DnaJ peptide-binding domain
ModBase Predicted Comparative 3D Structure on Q6FHS4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC002352 - Homo sapiens DnaJ (Hsp40) homolog, subfamily B, member 1, mRNA (cDNA clone MGC:8425 IMAGE:2821008), complete cds.BC013157 - Homo sapiens cDNA clone IMAGE:3919249, containing frame-shift errors.AK092989 - Homo sapiens cDNA FLJ35670 fis, clone SPLEN2018159, moderately similar to HEAT SHOCK 40 KDA PROTEIN 1.D49547 - Homo sapiens hsp40 mRNA for heat-shock protein 40, complete cds.JD087677 - Sequence 68701 from Patent EP1572962.JD379793 - Sequence 360817 from Patent EP1572962.JD563385 - Sequence 544409 from Patent EP1572962.JD548513 - Sequence 529537 from Patent EP1572962.JD049225 - Sequence 30249 from Patent EP1572962.JD181482 - Sequence 162506 from Patent EP1572962.JD342837 - Sequence 323861 from Patent EP1572962.JD315071 - Sequence 296095 from Patent EP1572962.JD547195 - Sequence 528219 from Patent EP1572962.JD378540 - Sequence 359564 from Patent EP1572962.JD561647 - Sequence 542671 from Patent EP1572962.AK296609 - Homo sapiens cDNA FLJ52967 complete cds, highly similar to DnaJ homolog subfamily B member 1.JD425008 - Sequence 406032 from Patent EP1572962.JD116265 - Sequence 97289 from Patent EP1572962.X62421 - Homo sapiens mRNA for DnaJ protein homologue.JD527518 - Sequence 508542 from Patent EP1572962.JD355991 - Sequence 337015 from Patent EP1572962.AK301817 - Homo sapiens cDNA FLJ59093 complete cds, highly similar to DnaJ homolog subfamily B member 1.JD488359 - Sequence 469383 from Patent EP1572962.JD493915 - Sequence 474939 from Patent EP1572962.LF208170 - JP 2014500723-A/15673: Polycomb-Associated Non-Coding RNAs.BC019827 - Homo sapiens DnaJ (Hsp40) homolog, subfamily B, member 1, mRNA (cDNA clone MGC:29935 IMAGE:4152608), complete cds.JD386399 - Sequence 367423 from Patent EP1572962.JD526527 - Sequence 507551 from Patent EP1572962.DL491965 - Novel nucleic acids.DL490522 - Novel nucleic acids.JD252908 - Sequence 233932 from Patent EP1572962.KJ891407 - Synthetic construct Homo sapiens clone ccsbBroadEn_00801 DNAJB1 gene, encodes complete protein.CR536485 - Homo sapiens full open reading frame cDNA clone RZPDo834C0320D for gene DNAJB1, DnaJ (Hsp40) homolog, subfamily B, member 1; complete cds, incl. stopcodon.AK312624 - Homo sapiens cDNA, FLJ93008, Homo sapiens DnaJ (Hsp40) homolog, subfamily B, member 1 (DNAJB1),mRNA.CR541677 - Homo sapiens full open reading frame cDNA clone RZPDo834C0428D for gene DNAJB1, DnaJ (Hsp40) homolog, subfamily B, member 1; complete cds, without stopcodon.AB463573 - Synthetic construct DNA, clone: pF1KB5377, Homo sapiens DNAJB1 gene for DnaJ (Hsp40) homolog, subfamily B, member 1, without stop codon, in Flexi system.CU676466 - Synthetic construct Homo sapiens gateway clone IMAGE:100018148 5' read DNAJB1 mRNA.LF373210 - JP 2014500723-A/180713: Polycomb-Associated Non-Coding RNAs.MA608787 - JP 2018138019-A/180713: Polycomb-Associated Non-Coding RNAs.MA443747 - JP 2018138019-A/15673: Polycomb-Associated Non-Coding RNAs.MP015449 - Sequence 652 from Patent WO2019016252.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: DNAJB1 , ENST00000254322.1, ENST00000254322.2, hCG_1776318 , NM_006145, Q6FHS4, Q6FHS4_HUMAN, uc317fob.1, uc317fob.2UCSC ID: ENST00000254322.3_7RefSeq Accession: NM_006145.3
Protein: Q6FHS4
Gene Model Information
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.