ID:DNJB4_HUMAN DESCRIPTION: RecName: Full=DnaJ homolog subfamily B member 4; AltName: Full=Heat shock 40 kDa protein 1 homolog; Short=HSP40 homolog; Short=Heat shock protein 40 homolog; AltName: Full=Human liver DnaJ-like protein; FUNCTION: Probable chaperone. SUBUNIT: Homodimer. The C-terminal section interacts with the C- terminal tail of OPRM1. Interacts also with SDIM1. SUBCELLULAR LOCATION: Cytoplasm. Cell membrane. Note=Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645. TISSUE SPECIFICITY: Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver. INDUCTION: By heat shock. SIMILARITY: Contains 1 J domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9UDY4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006457 protein folding GO:0006986 response to unfolded protein GO:0009408 response to heat GO:0032781 positive regulation of ATPase activity