Human Gene ENKD1 (ENST00000243878.9_7) from GENCODE V47lift37
  Description: enkurin domain containing 1, transcript variant 2 (from RefSeq NR_138150.2)
Gencode Transcript: ENST00000243878.9_7
Gencode Gene: ENSG00000124074.12_9
Transcript (Including UTRs)
   Position: hg19 chr16:67,696,848-67,700,653 Size: 3,806 Total Exon Count: 7 Strand: -
Coding Region
   Position: hg19 chr16:67,697,064-67,700,345 Size: 3,282 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:67,696,848-67,700,653)mRNA (may differ from genome)Protein (346 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIPubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: CP048_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C16orf48;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 50.84 RPKM in Testis
Total median expression: 750.71 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -159.90308-0.519 Picture PostScript Text
3' UTR -80.20216-0.371 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF13864 - Calmodulin-binding

ModBase Predicted Comparative 3D Structure on Q9H0I2
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details Gene Details  
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-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

Cellular Component:
GO:0005881 cytoplasmic microtubule
GO:0015630 microtubule cytoskeleton


-  Descriptions from all associated GenBank mRNAs
  AY358834 - Homo sapiens clone DNA167659 DAKV6410 (UNQ6410) mRNA, complete cds.
BC008284 - Homo sapiens chromosome 16 open reading frame 48, mRNA (cDNA clone MGC:10689 IMAGE:3638194), complete cds.
AL136786 - Homo sapiens mRNA; cDNA DKFZp434A1319 (from clone DKFZp434A1319).
JD562787 - Sequence 543811 from Patent EP1572962.
JD320120 - Sequence 301144 from Patent EP1572962.
JD114403 - Sequence 95427 from Patent EP1572962.
AM393079 - Synthetic construct Homo sapiens clone IMAGE:100001715 for hypothetical protein (C16orf48 gene).
KJ894934 - Synthetic construct Homo sapiens clone ccsbBroadEn_04328 C16orf48 gene, encodes complete protein.
AB528083 - Synthetic construct DNA, clone: pF1KE0111, Homo sapiens C16orf48 gene for chromosome 16 open reading frame 48, without stop codon, in Flexi system.
JD466458 - Sequence 447482 from Patent EP1572962.
JD399388 - Sequence 380412 from Patent EP1572962.
JD473131 - Sequence 454155 from Patent EP1572962.
JD343313 - Sequence 324337 from Patent EP1572962.
JD206324 - Sequence 187348 from Patent EP1572962.
JD408717 - Sequence 389741 from Patent EP1572962.
JD068139 - Sequence 49163 from Patent EP1572962.
JD218431 - Sequence 199455 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C16orf48, ENKD1_HUMAN, ENST00000243878.1, ENST00000243878.2, ENST00000243878.3, ENST00000243878.4, ENST00000243878.5, ENST00000243878.6, ENST00000243878.7, ENST00000243878.8, NR_138150, Q6UWD7, Q9H0I2, uc317ena.1, uc317ena.2, UNQ6410/PRO21183
UCSC ID: ENST00000243878.9_7
RefSeq Accession: NM_032140.3
Protein: Q9H0I2 (aka CP048_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.