Human Gene EPDR1 (ENST00000199448.9_7) from GENCODE V47lift37
Description: ependymin related 1, transcript variant 1 (from RefSeq NM_017549.5)
Gencode Transcript: ENST00000199448.9_7
Gencode Gene: ENSG00000086289.13_12
Transcript (Including UTRs)
Position: hg19 chr7:37,960,242-37,991,538 Size: 31,297 Total Exon Count: 3 Strand: +
Coding Region
Position: hg19 chr7:37,960,542-37,989,998 Size: 29,457 Coding Exon Count: 3
Data last updated at UCSC: 2024-08-22 23:36:26
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: EPDR1_HUMAN
DESCRIPTION: RecName: Full=Mammalian ependymin-related protein 1; Short=MERP-1; AltName: Full=Upregulated in colorectal cancer gene 1 protein; Flags: Precursor;
SUBCELLULAR LOCATION: Secreted.SIMILARITY: Belongs to the ependymin family.SEQUENCE CAUTION: Sequence=AAH00686.2; Type=Erroneous initiation; Sequence=CAB60269.1; Type=Erroneous initiation;
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001299 - Ependymin
IPR018224 - Ependymin_CS
Pfam Domains: PF00811 - Ependymin
ModBase Predicted Comparative 3D Structure on Q9UM22
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AY027862 - Homo sapiens mammalian ependymin related protein 1 (MERP1) mRNA, complete cds.BC018299 - Homo sapiens ependymin related protein 1 (zebrafish), mRNA (cDNA clone MGC:17297 IMAGE:3461888), complete cds.BC000686 - Homo sapiens ependymin related protein 1 (zebrafish), mRNA (cDNA clone IMAGE:3347737), partial cds.AK290885 - Homo sapiens cDNA FLJ78572 complete cds, highly similar to Homo sapiens ependymin related protein-1 (MERP1) gene.KJ902679 - Synthetic construct Homo sapiens clone ccsbBroadEn_12073 EPDR1 gene, encodes complete protein.DQ914439 - Homo sapiens mammalian ependymin protein 1a (EPDR1) mRNA, complete cds, alternatively spliced.JD192911 - Sequence 173935 from Patent EP1572962.JD230680 - Sequence 211704 from Patent EP1572962.JD426351 - Sequence 407375 from Patent EP1572962.AJ250475 - Homo sapiens mRNA for UCC1 protein (UCC1 gene).AK309180 - Homo sapiens cDNA, FLJ99221.JD460532 - Sequence 441556 from Patent EP1572962.JD436201 - Sequence 417225 from Patent EP1572962.JD043378 - Sequence 24402 from Patent EP1572962.JD452372 - Sequence 433396 from Patent EP1572962.JD270084 - Sequence 251108 from Patent EP1572962.JD336129 - Sequence 317153 from Patent EP1572962.JD192217 - Sequence 173241 from Patent EP1572962.JD116043 - Sequence 97067 from Patent EP1572962.JD393641 - Sequence 374665 from Patent EP1572962.JD554070 - Sequence 535094 from Patent EP1572962.JD322217 - Sequence 303241 from Patent EP1572962.JD132899 - Sequence 113923 from Patent EP1572962.JD132900 - Sequence 113924 from Patent EP1572962.JD493784 - Sequence 474808 from Patent EP1572962.JD512389 - Sequence 493413 from Patent EP1572962.JD561107 - Sequence 542131 from Patent EP1572962.JD510356 - Sequence 491380 from Patent EP1572962.JD081385 - Sequence 62409 from Patent EP1572962.JD048955 - Sequence 29979 from Patent EP1572962.AX229887 - Sequence 13 from Patent WO0162959.JD552519 - Sequence 533543 from Patent EP1572962.JD206401 - Sequence 187425 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A8K4C0, C9JYS3, ENST00000199448.1, ENST00000199448.2, ENST00000199448.3, ENST00000199448.4, ENST00000199448.5, ENST00000199448.6, ENST00000199448.7, ENST00000199448.8, EPDR1_HUMAN, MERP1, NM_017549, Q06BL0, Q99M77, Q9UM22, uc317chl.1, uc317chl.2, UCC1UCSC ID: ENST00000199448.9_7RefSeq Accession: NM_017549.5
Protein: Q9UM22
(aka EPDR1_HUMAN)
Gene Model Information
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for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.