Human Gene FAM169A (ENST00000687041.1_4) from GENCODE V47lift37
  Description: family with sequence similarity 169 member A, transcript variant 10 (from RefSeq NR_164754.1)
Gencode Transcript: ENST00000687041.1_4
Gencode Gene: ENSG00000198780.13_14
Transcript (Including UTRs)
   Position: hg19 chr5:74,073,399-74,162,212 Size: 88,814 Total Exon Count: 13 Strand: -
Coding Region
   Position: hg19 chr5:74,077,285-74,137,501 Size: 60,217 Coding Exon Count: 12 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:74,073,399-74,162,212)mRNA (may differ from genome)Protein (670 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsHGNC
MGIOMIMPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: F169A_HUMAN
DESCRIPTION: RecName: Full=Protein FAM169A;
SIMILARITY: Belongs to the FAM169 family.
SEQUENCE CAUTION: Sequence=BAA74911.1; Type=Erroneous initiation; Sequence=BAB14344.1; Type=Erroneous initiation; Sequence=CAE45948.1; Type=Erroneous initiation;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
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+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -122.50226-0.542 Picture PostScript Text
3' UTR -864.103886-0.222 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  SCOP Domains:
55729 - Acyl-CoA N-acyltransferases (Nat)

ModBase Predicted Comparative 3D Structure on Q9Y6X4
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
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-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005637 nuclear inner membrane
GO:0016020 membrane


-  Descriptions from all associated GenBank mRNAs
  CR936791 - Homo sapiens mRNA; cDNA DKFZp781C2356 (from clone DKFZp781C2356).
BC040298 - Homo sapiens KIAA0888 protein, mRNA (cDNA clone IMAGE:4819660).
BC044766 - Homo sapiens KIAA0888 protein, mRNA (cDNA clone IMAGE:4821409).
BX647536 - Homo sapiens mRNA; cDNA DKFZp686E0692 (from clone DKFZp686E0692).
BX640902 - Homo sapiens mRNA; cDNA DKFZp686O1754 (from clone DKFZp686O1754).
AK022981 - Homo sapiens cDNA FLJ12919 fis, clone NT2RP2004587, weakly similar to NEUROFILAMENT TRIPLET M PROTEIN.
AB020695 - Homo sapiens KIAA0888 mRNA for KIAA0888 protein.
JD267736 - Sequence 248760 from Patent EP1572962.
JD115077 - Sequence 96101 from Patent EP1572962.
AK290004 - Homo sapiens cDNA FLJ77271 complete cds.
AB384035 - Synthetic construct DNA, clone: pF1KSDA0888, Homo sapiens KIAA0888 gene for KIAA0888 protein, complete cds, without stop codon, in Flexi system.
JD211621 - Sequence 192645 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A8K1T9, F169A_HUMAN, KIAA0888, NR_164754, Q6MZT0, Q9H989, Q9Y6X4, uc330qhk.1, uc330qhk.2
UCSC ID: ENST00000687041.1_4
RefSeq Accession: NM_001376049.1
Protein: Q9Y6X4 (aka F169A_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.