Human Gene PSME3IP1 (ENST00000309137.13_7) from GENCODE V47lift37
  Description: proteasome activator subunit 3 interacting protein 1, transcript variant 20 (from RefSeq NM_024946.4)
Gencode Transcript: ENST00000309137.13_7
Gencode Gene: ENSG00000172775.18_18
Transcript (Including UTRs)
   Position: hg19 chr16:57,186,378-57,219,951 Size: 33,574 Total Exon Count: 7 Strand: -
Coding Region
   Position: hg19 chr16:57,188,202-57,207,766 Size: 19,565 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:57,186,378-57,219,951)mRNA (may differ from genome)Protein (254 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
OMIMPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: F192A_HUMAN
DESCRIPTION: RecName: Full=Protein FAM192A; AltName: Full=NEFA-interacting nuclear protein NIP30;
SUBCELLULAR LOCATION: Nucleus (Potential).

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 28.37 RPKM in Testis
Total median expression: 950.65 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -71.40234-0.305 Picture PostScript Text
3' UTR -543.801824-0.298 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR019331 - Nefa_Nip30_N

Pfam Domains:
PF10187 - FAM192A/Fyv6, N-terminal domain

ModBase Predicted Comparative 3D Structure on Q9GZU8
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
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-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

Cellular Component:
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  AK023291 - Homo sapiens cDNA FLJ13229 fis, clone OVARC1000106.
JD292115 - Sequence 273139 from Patent EP1572962.
JD065792 - Sequence 46816 from Patent EP1572962.
JD432754 - Sequence 413778 from Patent EP1572962.
JD555575 - Sequence 536599 from Patent EP1572962.
JD449418 - Sequence 430442 from Patent EP1572962.
JD093012 - Sequence 74036 from Patent EP1572962.
AK025452 - Homo sapiens cDNA: FLJ21799 fis, clone HEP00611.
AF271785 - Homo sapiens CDA018 mRNA, complete cds.
AF212249 - Homo sapiens CDA10 mRNA, complete cds.
AF356585 - Homo sapiens NEFA-interacting nuclear protein NIP30 (NIP30) mRNA, complete cds.
BC071952 - Homo sapiens NEFA-interacting nuclear protein NIP30, mRNA (cDNA clone MGC:88642 IMAGE:6305656), complete cds.
BC063409 - Homo sapiens NEFA-interacting nuclear protein NIP30, mRNA (cDNA clone IMAGE:5211300), complete cds.
JD424735 - Sequence 405759 from Patent EP1572962.
JD354478 - Sequence 335502 from Patent EP1572962.
JD156683 - Sequence 137707 from Patent EP1572962.
JD301429 - Sequence 282453 from Patent EP1572962.
JD450293 - Sequence 431317 from Patent EP1572962.
JD547242 - Sequence 528266 from Patent EP1572962.
JD144978 - Sequence 126002 from Patent EP1572962.
JD501928 - Sequence 482952 from Patent EP1572962.
BC020536 - Homo sapiens NEFA-interacting nuclear protein NIP30, mRNA (cDNA clone MGC:21022 IMAGE:3849620), complete cds.
AL834421 - Homo sapiens mRNA; cDNA DKFZp667A136 (from clone DKFZp667A136).
DQ891689 - Synthetic construct clone IMAGE:100004319; FLH180046.01X; RZPDo839F04132D NEFA-interacting nuclear protein NIP30 (NIP30) gene, encodes complete protein.
KJ894770 - Synthetic construct Homo sapiens clone ccsbBroadEn_04164 FAM192A gene, encodes complete protein.
DQ894983 - Synthetic construct Homo sapiens clone IMAGE:100009443; FLH180043.01L; RZPDo839F04131D NEFA-interacting nuclear protein NIP30 (NIP30) gene, encodes complete protein.
AB528823 - Synthetic construct DNA, clone: pF1KE0417, Homo sapiens NIP30 gene for family with sequence similarity 192, member A, without stop codon, in Flexi system.
AM393111 - Synthetic construct Homo sapiens clone IMAGE:100001874 for hypothetical protein (NIP30 gene).
AM393361 - Synthetic construct Homo sapiens clone IMAGE:100001867 for hypothetical protein (NIP30 gene).
KJ903265 - Synthetic construct Homo sapiens clone ccsbBroadEn_12659 FAM192A gene, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: C16orf94 , CDA018, CDA10, ENST00000309137.1, ENST00000309137.10, ENST00000309137.11, ENST00000309137.12, ENST00000309137.2, ENST00000309137.3, ENST00000309137.4, ENST00000309137.5, ENST00000309137.6, ENST00000309137.7, ENST00000309137.8, ENST00000309137.9, FAM192A, NIP30 , NM_024946, PIP30 , PIP30_HUMAN, PSME3IP1 , Q9GZU8, uc317olr.1, uc317olr.2
UCSC ID: ENST00000309137.13_7
RefSeq Accession: NM_024946.4
Protein: Q9GZU8 (aka F192A_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.