The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8NEZ5
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0004842 ubiquitin-protein transferase activity GO:0005515 protein binding
Biological Process: GO:0000209 protein polyubiquitination GO:0006464 cellular protein modification process GO:0006511 ubiquitin-dependent protein catabolic process GO:0006913 nucleocytoplasmic transport GO:0009267 cellular response to starvation GO:0010830 regulation of myotube differentiation GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0043687 post-translational protein modification GO:0048742 regulation of skeletal muscle fiber development GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
