The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 47454 - A DNA-binding domain in eukaryotic transcription factors 57959 - Leucine zipper domain
ModBase Predicted Comparative 3D Structure on Q6FG41
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0003677 DNA binding GO:0003682 chromatin binding GO:0003690 double-stranded DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding GO:0005515 protein binding GO:0008134 transcription factor binding GO:0043565 sequence-specific DNA binding GO:0046982 protein heterodimerization activity
Biological Process: GO:0001661 conditioned taste aversion GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0006366 transcription from RNA polymerase II promoter GO:0007399 nervous system development GO:0007565 female pregnancy GO:0007568 aging GO:0009409 response to cold GO:0009416 response to light stimulus GO:0009612 response to mechanical stimulus GO:0009629 response to gravity GO:0009636 response to toxic substance GO:0014070 response to organic cyclic compound GO:0030431 sleep GO:0031668 cellular response to extracellular stimulus GO:0032496 response to lipopolysaccharide GO:0032570 response to progesterone GO:0032870 cellular response to hormone stimulus GO:0034097 response to cytokine GO:0035902 response to immobilization stress GO:0035914 skeletal muscle cell differentiation GO:0035994 response to muscle stretch GO:0042493 response to drug GO:0045672 positive regulation of osteoclast differentiation GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0051412 response to corticosterone GO:0051591 response to cAMP GO:0071277 cellular response to calcium ion GO:1901216 positive regulation of neuron death GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
