ID:GSCR2_HUMAN DESCRIPTION: RecName: Full=Glioma tumor suppressor candidate region gene 2 protein; AltName: Full=p60; SUBUNIT: Interacts with HSV-1 early proteins ICP22 and ICP0. SUBCELLULAR LOCATION: Nucleus, nucleolus. TISSUE SPECIFICITY: Expressed at high levels in heart and pancreas, moderate levels in placenta, liver, skeletal muscle, and kidney, and low levels in brain and lung. SIMILARITY: Belongs to the GLTSCR2 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NZM5
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0000027 ribosomal large subunit assembly GO:0000055 ribosomal large subunit export from nucleus GO:0000122 negative regulation of transcription from RNA polymerase II promoter GO:0001932 regulation of protein phosphorylation GO:0006281 DNA repair GO:0006974 cellular response to DNA damage stimulus GO:0007095 mitotic G2 DNA damage checkpoint GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling GO:0031333 negative regulation of protein complex assembly GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0039535 regulation of RIG-I signaling pathway GO:0042254 ribosome biogenesis GO:0042981 regulation of apoptotic process GO:0050821 protein stabilization GO:0051726 regulation of cell cycle GO:0051898 negative regulation of protein kinase B signaling GO:0071456 cellular response to hypoxia GO:1901796 regulation of signal transduction by p53 class mediator GO:1901797 negative regulation of signal transduction by p53 class mediator GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter GO:1902570 protein localization to nucleolus GO:1903006 positive regulation of protein K63-linked deubiquitination GO:1903715 regulation of aerobic respiration GO:1990173 protein localization to nucleoplasm
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
